锌指结构蛋白酶20抗体

英文名称    ZDHHC20    

中文名称    锌指结构蛋白酶20抗体    

别    名    DHHC-20; Probable palmitoyltransferase ZDHHC20; ZDH20_HUMAN; ZDHHC20; Zinc finger DHHC domain-containing protein 20.    

说 明 书    0.2ml      

研究领域    细胞生物  通道蛋白  细胞膜蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 锌指结构蛋白酶20抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    42kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human DHHC-20    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

锌指结构蛋白酶20抗体产品介绍    background:

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC20 (zinc finger, DHHC-type containing 20) is a 365 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to an S-palmitoyl protein and free CoA. In response to DNA damage, ZDHHC20, which exists as multiple alternatively spliced isoforms, may be phosphorylated by ATM or ATR. The gene encoding ZDHHC20 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. 

Function:
Belongs to the DHHC palmitoyltransferase family. Contains 1 DHHC-type zinc finger.

Subcellular Location:
Membrane; Multi-pass membrane protein (Potential). 

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the DHHC palmitoyltransferase family. 
Contains 1 DHHC-type zinc finger.     

锌指结构蛋白酶20抗体

hz-1197P TLR5/CD285 (Toll-like receptor 5)  Toll样受体5抗原

hz-0525P TM(Thrombomodulin)  血栓调节蛋白多肽

hz-1327P Tn-C(Tenascin-C)C-Terminus  腱糖蛋白-C(固生蛋白)C端抗原

hz-2081P TNF-alpha  肿瘤坏死因子-α抗原

hz-0093P TNF- Beta(Tumor Necrosis Factor- Beta)  肿瘤坏死因子-β抗原

hz-2104P TNFAIP1(Tumor necrosis factor-alpha-induced protein 1)  肿瘤坏死因子α诱导蛋白1抗原

hz-0905P Acetylated-P53(Lys382) peptide  抗肿瘤P53抗原

hz-1211P TP I (topoisomerase I )  拓普西异构酶Ⅰ抗原

hz-1203P TOPO II Alpha/DNA TP II Alpha (DNA topoisomerase II Alpha)  DNA拓普西异构酶Ⅱ抗原

hz-1215P TPH (Trptophan Hydroxylase)  色氨酸羟化酶(多肽)

hz-0329P TRA16 (Testicular orphan nuclear receptor-4 (TR4)-associated protein)  睾丸激素受体相关蛋白/孤儿素受体相关蛋白(抗原)

hz-1202P TRADD(TNF receptor 1 associated via death domain)  有死亡区的肿瘤坏死因子受体1相关蛋白抗原

hz-1212P TRAF1  肿瘤坏死因子受体相关因子1抗原

hz-1213P TRAF2/TNF-R2 (TNF receptor-associated factor 2)  肿瘤坏死因子受体相关因子2抗原

hz-1185P TRAF3/CD40bp (CD40 binding protein)  肿瘤坏死因子受体相关蛋白3抗原

hz-1184P TRAF6 (TNF receptor-associated factor 6)  肿瘤坏死因子受体相关因子6抗原

hz-1214P TRAIL/Apo2L (tumor necrosis factor-related apoptosis-inducing ligand)  肿瘤坏死因子相关凋亡诱导配体/凋亡素2配体抗原

hz-1151P TRBF1 (Telomeric repeat binding factor 1)  端粒体复制结合因子1抗原

hz-0964P TRIM32(tripartite motif protein 32)  TRIM32抗原

hz-1243P Trop-2/Tpm2 peptide  原肌球蛋白抗原

hz-1220P TSARG4(Testis and spermatogenesis related gene 4)  生精细胞凋亡相关基因4抗原

hz-0546P TSGF(Tumor Specific Growth Fanctor)  恶性肿瘤特异性生长因子抗原

hz-0716P CIDEB peptide  CIDEB抗原

hz-1365P Tsg101(Tumor susceptibility gene 101 protein)  Tsg101抗原

hz-2087P TSHR (Thyroid stimulating hormone receptor)  促甲状腺素受体抗原

hz-1534P MAP1LC3A(microtubule-associated protein 1 light chain 3)  自噬微管相关蛋白轻链3抗原

hz-1147P TSLC1 (tumor suppressor in lung cancer-1)  肺癌肿瘤阻抑基因1抗原

hz-0826P TTF-1 (Thyroid Transcription Factor-1)  甲状腺核转录因子-1抗原

hz-1322P Tubulin- Gamma  微管蛋白-γ抗原

hz-2441P TWIST protein peptide  TWIST蛋白抗原

hz-1088P T Beta10 peptide  胸腺素β10抗原

hz-1929P UCN(Urocortin)mouse ret  新型血管活性因子UCN抗原(小鼠、大鼠)

hz-1403P USF-1(upstream stimulatory factor 1)  上游刺激因子1抗原

hz-1549P Ubiquitin  泛素蛋白