英文名称 ERR-alpha
中文名称 雌激素受体相关蛋白α抗体
别 名 Estrogen Related Receptor alpha; ERR-α; ERR α; ERRα; ERR alpha; Err 1; ERR a; ERR alpha; ERR-alpha; Err1; ERR1_HUMAN; ERRa; ERRalpha; ESRL 1; ESRL1; ESRR A; Esrra; Estrogen receptor like 1; Estrogen receptor related 1; Estrogen receptor-like 1; Estrogen related receptor alpha; Estrogen-related receptor alpha; Estrra; Nr3b1; Nuclear receptor subfamily 3 group B member 1; Steroid hormone receptor ERR1.
说 明 书 0.2ml
研究领域 肿瘤 细胞生物 染色质和核信号 信号转导 生长因子和激素 结合蛋白 细胞骨架 表观遗传学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 雌激素受体相关蛋白α抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
细胞定位 细胞核
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Estrogen Related Receptor alpha
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
雌激素受体相关蛋白α抗体产品介绍 background:
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism.
Subunit:
Binds DNA as a monomer or a homodimer. Interacts (via the AF2 domain) with coactivator PPARGC1A (via the L3 motif); the interaction greatly enhances transriptional activity of genes involved in energy metabolism. Interacts with PIAS4; the interaction enhances sumoylation.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the nuclear hormone receptor family. NR3 subfamily.
Contains 1 nuclear receptor DNA-binding domain.
雌激素受体相关蛋白α抗体
hz-1602R SPA-1/SIPA-1 信号感应增殖相关蛋白1抗体
hz-0717R SPAG5/MAP126/Astrin 精子相关抗原5抗体
hz-1133R SPARC 富含半胱氨酸的酸性分泌蛋白抗体
hz-1034R SP-B 肺表面活性蛋白B抗体
hz-2337R SP-C 肺表面活性蛋白C抗体
hz-1583R SP-D/PSPD 肺表面活性蛋白D抗体
hz-0381R alpha 1 Spectrin/Spectrin α 血影蛋白/收缩蛋白抗体
hz-2675R SPECA a-包衬蛋白抗体
hz-2652R SPHK1 鞘氨醇激酶1抗体
hz-2653R SPHK2 鞘氨醇激酶2抗体
hz-0724R Spindlin 1 卵巢癌相关蛋白抗体
hz-0873R SPY/CCDC99 卷曲螺旋结构域蛋白99抗体
hz-1518R Persephin PSP抗体
hz-1135R SRC src原癌基因抗体
hz-3408R Phospho-SRC-3 (Thr24) 磷酸化类固醇受体辅助活化因子-3
hz-1730R phospho-Src(Tyr529) 磷酸化Src原癌基因抗体
hz-3426R phospho-Src(Tyr418) 磷酸化Src原癌基因抗体
hz-5624R phospho-Src(Tyr215) 磷酸化Src原癌基因抗体
hz-1401R SRF/SAP2/MCM1 生长激素释放因子抗体(血清应答因子)
hz-3409R Phospho-SRF (Ser103) 磷酸化生长激素释放因子抗体(血清应答因子)
hz-1402R SREBP-1 胆固醇调节元件结合蛋白1抗体
hz-2536R SREBP-2 胆固醇调节元件结合蛋白2抗体
hz-3660R srGAP3 精神障碍相关GAP蛋白抗体
hz-1136R synaptotagmin-2 突触结合蛋白相关基因2抗体
hz-1897R Synaptotagmin-4 突触结合蛋白4抗体
hz-3972R Synaptotagmin 5 突触结合蛋白5抗体
hz-1898R SPATA12 睾丸特异表达新基因5抗体
hz-1899R SRG11/Spata17 睾丸凋亡基因抗体
hz-3633R Synaptopodin 突触极蛋白synaptopodin抗体
hz-0635R SSA/52KDa Ro 核糖核蛋白抗原抗体
hz-0276R SSB/La 干燥症SSB/La抗体
hz-5818R Sulfatase 1 硫酸酯酶1抗体
hz-3857R SSDD/Steroid sulfatase 类固醇硫酸酯酶抗体
hz-3894R Sulfatase 2 硫酸酯酶2蛋白抗体