英文名称 DAD1
中文名称 细胞死亡防卫蛋白1抗体
别 名 DAD 1; DAD-1; dad1; DAD1_HUMAN; Defender against cell death 1; Dolichyl diphosphooligosaccharide protein glycosyltransferase subunit DAD1; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Oligosaccharyl transferase subunit DAD1; OST 2; OST2.
说 明 书 0.2ml
研究领域 细胞生物 信号转导 细胞凋亡
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 细胞死亡防卫蛋白1抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12kDa
细胞定位 细胞浆 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DAD1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
细胞死亡防卫蛋白1抗体产品介绍 background:
Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis.
Function:
Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis (By similarity).
Subunit:
Component of the oligosaccharyltransferase (OST) complex. OST seems to exist in different forms which contain at least RPN1, RPN2, OST48, DAD1, OSTC, KRTCAP2 and either STT3A or STT3B. OST can form stable complexes with the Sec61 complex or with both the Sec61 and TRAP complexes (By similarity).
Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity).
Similarity:
Belongs to the DAD/OST2 family.
Database links:
UniProtKB/Swiss-Prot: P61803.3
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞死亡防卫蛋白1抗体
hz-0595R DMBT1 抑癌基因抗体
hz-5842R MIIP IGFBP2结合蛋白/迁移和侵润抑制蛋白抗体
hz-4100R DNM1L 发动蛋白样相关蛋白1抗体
hz-2092R DNA PK/PRKDC DNA依赖性蛋白激酶抗体
hz-3734R phospho-DNA PK/PRKDC(Ser2056) 磷酸化DNA依赖性蛋白激酶抗体
hz-3735R phospho-DNA PK/PRKDC(Thr2609) 磷酸化DNA依赖性蛋白激酶抗体
hz-5568R phospho-DNA PK/PRKDC(Ser2612) 磷酸化DNA依赖性蛋白激酶抗体
hz-0678R Dnmt1 DNA甲基转移酶1抗体
hz-5844R SMAGP 小细胞跨膜糖化蛋白抗体
hz-5294R phospho-Dnmt1(Ser154) 磷酸化DNA甲基转移酶1抗体
hz-5295R phospho-Dnmt1(Ser732) 磷酸化DNA甲基转移酶1抗体
hz-5296R phospho-Dnmt1(Tyr399) 磷酸化DNA甲基转移酶1抗体
hz-5297R phospho-Dnmt1(Tyr969) 磷酸化DNA甲基转移酶1抗体
hz-0497R Dnmt3a DNA甲基转移酶-3α抗体
hz-5845R TAG1/CNTN2 瞬时表达轴索糖蛋白1抗体
hz-5847R ADAM12/MLTN 去整合素样金属蛋白酶12抗体
hz-0301R Dnmt3 Beta DNA甲基转移酶-3β抗体
hz-1359R DNAPK/PRKDC DNA依赖蛋白激酶催化亚基抗体
hz-2102R DNPK1 DNA依赖蛋白激酶催化亚基抗体
hz-3794R DOG-1/TMhz16A 跨膜蛋白16A/钙激活氯离子通道抗体
hz-1467R DOK1 D酪氨酸激酶衰减蛋白1抗体
hz-5289R phospho-DOK1(Tyr362) 磷酸化D酪氨酸激酶衰减蛋白1抗体
hz-5290R phospho-DOK1 (Tyr398) 磷酸化D酪氨酸激酶衰减蛋白1抗体
hz-2746R DOK2 D酪氨酸激酶衰减蛋白2抗体
hz-3101R Phospho-p56Dok2(Tyr351) 磷酸化D酪氨酸激酶衰减蛋白2抗体
hz-3102R Phospho-p56Dok2(Tyr299) 磷酸化D酪氨酸激酶衰减蛋白2抗体
hz-3103R Phospho-p56Dok2(Tyr142) 磷酸化D酪氨酸激酶衰减蛋白2抗体
hz-5143R DP1/TFDP1 转录因子DP1抗体
hz-0597R DPPA2/PESCRG1 多能发育相关基因2抗体
hz-5848R ADAM15 去整合素样金属蛋白酶15抗体
hz-0421R DR3/APO3/TWEAK 死亡受体3抗体
hz-5849R ADAM18 去整合素样金属蛋白酶18抗体
hz-5850R ADAM19 去整合素样金属蛋白酶19抗体