英文名称 DBC2
中文名称 乳腺癌基因删除蛋白2抗体
别 名 DBC 2; Deleted in breast cancer 2; Deleted in breast cancer 2 gene protein; E130206H14Rik; KIAA0717; p83; RBT2; RHBT2_HUMAN; Rho related BTB domain containing 2; Rho related BTB domain containing protein 2; Rho-related BTB domain containing 2; Rho-related BTB domain-containing protein 2; RHOBTB 2; Rhobtb2.
说 明 书 0.2ml
研究领域 肿瘤 细胞生物 免疫学 信号转导 细胞周期蛋白
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 乳腺癌基因删除蛋白2抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 83kDa
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DBC2
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
乳腺癌基因删除蛋白2抗体产品介绍 background:
DBC2 is a member of the recently identified RhoBTB family, which is part of the Rho GTPase family. DBC2 has been implicated as a tumor suppressor in breast and lung cancer. Studies have shown that DBC2 binds to the ubiquitin ligase scaffold Cul3, and that Cul3 regulates DBC2 protein levels by ubiquitinating DBC2 directly, leading to its degradation by the proteasome.
Tissue Specificity:
Ubiquitous, with highest levels in neural tissues. Expression is also detected in fetal lung, heart, and brain.
Similarity:
Belongs to the small GTPase superfamily. Rho family.
Contains 2 BTB (POZ) domains.
Database links:
UniProtKB/Swiss-Prot: Q9BYZ6.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
乳腺癌基因删除蛋白2抗体
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hz-11110R PCDH17 原钙粘附蛋白17抗体
hz-11111R PCDH1 原钙粘附蛋白1抗体
hz-11112R PCDH18 原钙粘附蛋白18抗体
hz-11113R PCDH20 原钙粘附蛋白20抗体
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hz-11115R PCDHA1 原钙粘附蛋白α1抗体
hz-11116R PCDHA2 原钙粘附蛋白α2抗体
hz-11117R PCDHA3 原钙粘附蛋白α3抗体
hz-11118R PCDHA4 原钙粘附蛋白α4抗体
hz-11119R PCDHA5 原钙粘附蛋白α5抗体
hz-11120R PCDHA9 原钙粘附蛋白α9抗体
hz-5366R phospho-GNA12(Ser68) 磷酸化鸟苷酸调节蛋白12抗体
hz-11121R PCDHA7 原钙粘附蛋白α7抗体
hz-11122R PCDHA8 原钙粘附蛋白α8抗体
hz-11123R PCDHA10/CNRN8 钙粘蛋白相关神经受体8抗体
hz-2586R ASIC1/BNaC2 酸敏感离子通道1抗体
hz-11124R PCDHA11 原钙粘蛋白11抗体
hz-11125R ROM1 视网膜感光细胞外节膜蛋白1抗体
hz-11126R PVRL1/CD111/Nectin1 脊髓灰质炎受体相关蛋白1抗体
hz-11127R CD11b/c equivalent CD11B/CD11C抗体
hz-11128R CASPR/Neurexin4 轴突蛋白4/少突胶质细胞抗体
hz-11129R Caspr2 轴突相关CNTP2蛋白抗体(少突胶质细胞)
hz-11130R VAT1L/KIAA1576 突触小泡膜蛋白同源样蛋白1抗体
hz-1282R ASPP1 p53凋亡刺激蛋白1抗体
hz-11131R LALBA/alpha Lactalbumin 乳清蛋白α抗体
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hz-11133R PCDHAC2 原钙粘蛋白介导的PCDHαC2受体抗体
hz-11134R PCDHB15/PCDHB22 原钙粘蛋白15抗体
hz-11135R PCDHB16 原钙粘蛋白16抗体
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