获取电话英文名称 DNA PKcs
中文名称 DNA依赖性蛋白激酶抗体
别 名 DNA-dependent protein kinase catalytic subunit; DNA-PK catalytic subunit; DNA-PKcs; DNA PKcs; DNPK1; p460; PRKDC; HYRC; HYRC1; Variant; DNAPK; DNAPK catalytic subunit; p350; PRKDC; Protein Kinase DNA Activated Catalytic Polypeptide; XRCC 7; XRCC7; PRKDC_HUMAN.
说 明 书 0.2ml
研究领域 肿瘤 细胞生物 免疫学 染色质和核信号 激酶和磷酸酶
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Chicken, Dog, Horse,
产品应用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 DNA依赖性蛋白激酶抗体（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 454kDa
细胞定位 细胞核
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNA PK
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DNA依赖性蛋白激酶抗体产品介绍 background:
This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]
Function:
Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage. Found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, thereby regulating DNA damage response mechanism. Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, MYC and RFA2. Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA. Ability to phosphorylate p53/TP53 in the presence of supercoiled DNA is dependent on C1D.
DNA依赖性蛋白激酶抗体
hz-9232R RNF167 环指蛋白167抗体
hz-9233R RNF180 环指蛋白180抗体
hz-9234R CREG1 E1A激活基因刺激蛋白1抗体
hz-9235R CDX1 尾侧型同源转录因子1抗体
hz-9236R CDX2/3 尾侧型同源转录因子2/3抗体
hz-9237R RNF35 环指蛋白35抗体
hz-9238R RNF23 环指蛋白23抗体
hz-9239R RNF24 环指蛋白24抗体
hz-9240R RNF25 环指蛋白25抗体
hz-9241R RNF31/HOIP 环指蛋白31抗体
hz-9242R RNF34 环指蛋白34抗体
hz-9243R RNF20 环指蛋白20抗体
hz-9244R RNF21 环指蛋白21抗体
hz-9245R RNF190 环指蛋白190抗体
hz-9246R RNF19B 环指蛋白19B抗体
hz-9247R RNF111 环指蛋白111抗体
hz-9248R RNF113A 环指蛋白113A抗体
hz-9249R RNF123 环指蛋白123抗体
hz-9250R TRAC1/RNF125 环指蛋白125抗体
hz-9251R RNF128 环指蛋白128抗体
hz-9252R RNF130/ 环指蛋白130抗体
hz-9253R RNF133 环指蛋白133抗体
hz-9254R RNF138 环指蛋白138抗体
hz-9255R RNF121 环指蛋白121抗体
hz-9256R RNF113B 环指蛋白113B抗体
hz-9257R RNF150 环指蛋白150抗体
hz-9258R RNF165 环指蛋白165抗体
hz-9259R RNF169 环指蛋白169抗体
hz-9260R RNF170 环指蛋白170抗体
hz-9261R RNF185 环指蛋白185抗体
hz-9262R RNF186 环指蛋白186抗体
hz-9264R RNF215 环指蛋白215抗体
hz-9265R RNF32 环指蛋白32抗体
hz-9266R USP9X 泛素特异性蛋白酶9X抗体
DNA依赖性蛋白激酶抗体 多少钱?
CST抗体/抗原的应用资料有吗？
CST抗体/抗原货号hz-2092R报价含票含运吗？
CST货号hz-2092R货期是多久？
沪震生物DNA依赖性蛋白激酶抗体 可以申请试用吗？
沪震生物CST抗体/抗原售后政策是什么？
DNA依赖性蛋白激酶抗体 有现货吗？
