C型凝集素结构域家族6成员A抗体

英文名称    DECTIN2    

中文名称    C型凝集素结构域家族6成员A抗体    

别    名    DECTIN-2; DECTIN 2; DECTIN2; C type lectin domain family 6 member A; C type lectin superfamily member 10; C-type lectin domain family 6 member A; C-type lectin superfamily member 10; CLC6A_HUMAN; CLEC4N; Clec6a; CLECSF10; DC associated C type lectin 2; DC-associated C-type lectin 2; Dectin-2; Dectin2; Dendritic cell associated lectin 2; Dendritic cell-associated C-type lectin 2.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  免疫学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Cow, Horse, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 C型凝集素结构域家族6成员A抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    24kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Dectin-2    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

C型凝集素结构域家族6成员A抗体产品介绍    background:

Dectin 2 is a type II transmembrane protein that is a member of the C type lectin superfamily. In mouse, dectin 2 is predominantly expressed on tissue macrophages and some dendritic cells. Significant expression of Dectin 2 has been reported on macrophages in the red pulp and marginal zones of the spleen, kupffer cells in the liver and alveolar macrophages in the lung. Peripheral blood monocytes express low levels of dectin 2 but transient up regulation of expression has been demonstrated on monocytes at sites of inflammation. The function of dectin 2 has not been fully determined but studies suggest a possible role in immune surveillance.

Function:
Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptative immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway (By similarity).     

C型凝集素结构域家族6成员A抗体

hz-8125R CCDC25  卷曲螺旋结构域蛋白25抗体

hz-8127R CCDC28A  卷曲螺旋结构域蛋白28A抗体

hz-8128R CCDC28B  卷曲螺旋结构域蛋白28B抗体

hz-8129R CCDC36/CT74  肿瘤/睾丸抗原74抗体

hz-8130R CCDC38  卷曲螺旋结构域蛋白38抗体

hz-8131R CCDC42  卷曲螺旋结构域蛋白42抗体

hz-8132R CCDC43  卷曲螺旋结构域蛋白43抗体

hz-8133R CCDC46  卷曲螺旋结构域蛋白46抗体

hz-8134R CCDC47  卷曲螺旋结构域蛋白47抗体

hz-8135R CCDC54/NYD-SP17  卷曲螺旋结构域蛋白54抗体

hz-2415R Ankyrin G  锚定蛋白G抗体

hz-8136R CCDC61  卷曲螺旋结构域蛋白61抗体

hz-8137R CCDC63  卷曲螺旋结构域蛋白63抗体

hz-8138R CCDC8  卷曲螺旋结构域蛋白8抗体

hz-8139R CCDC83  卷曲螺旋结构域蛋白83抗体

hz-8140R CCDC87  卷曲螺旋结构域蛋白87抗体

hz-2040R ANP  心钠素抗体

hz-8141R CCDC88B/BRLZ/HkRP3  大脑亮氨酸拉链结构域蛋白抗体

hz-8142R CCDC92  卷曲螺旋结构域蛋白92抗体

hz-8143R CCDC93  卷曲螺旋结构域蛋白93抗体

hz-8144R CCDC96  卷曲螺旋结构域蛋白96抗体

hz-8145R CHCHD5  卷曲螺旋结构域蛋白CHCHD5抗体

hz-8146R CHCHD6  卷曲螺旋结构域蛋白CHCHD6抗体

hz-8148R CHCHD8  卷曲螺旋结构域蛋白CHCHD8抗体

hz-8149R Slc22a5  溶质载体家族蛋白22成员5抗体

hz-8150R NPFF/FMRFamide  吗啡痛觉调节肽NPFF抗体

hz-8151R FAM36A  FAM36A蛋白抗体

hz-8152R FAM50A  FAM50A蛋白抗体

hz-8153R FAM134C  FAM134C蛋白抗体

hz-8154R Histone H2A.Z/ H2AFZ  组蛋白H2AZ抗体

hz-8155R GM130  高尔基体自身蛋白GM130抗体

hz-8156R FBRSL1  乙型肝炎病毒X蛋白反转录蛋白9抗体

hz-8157R GMRP1/BTBD10  糖代谢相关蛋白1抗体