获取电话英文名称 CYP27B1
中文名称 细胞色素P450 27B1抗体
别 名 1alpha(OH)ase; 25-hydroxyvitamin D(3) 1-alpha-hydroxylase; 25-hydroxyvitamin D-1 alpha hydroxylase; 25-OHD-1 alpha-hydroxylase; Calcidiol 1-monooxygenase; CP27B_HUMAN; CP2B; CYP1; CYP1ALPHA; CYP27B; Cyp27b1; Cytochrome p450 27B1; Cytochrome p450 27B13; Cytochrome P450 family 27 subfamily B polypeptide 1; Cytochrome P450 subfamily XXVIIB (25-hydroxyvitamin D-1-alpha-hydroxylase) polypeptide 1; Cytochrome P450 subfamily XXVIIB polypeptide 1; Cytochrome P450C1 alpha; Cytochrome P450VD1-alpha; mitochondrial; P450C1 alpha; P450c1; P450C1-alpha; P450VD1-alpha; PDDR; VD3 1A hydroxylase; VDD1; VDDR; VDDR I; VDDRI; VDR.
说 明 书 0.1ml 0.2ml
研究领域 细胞生物
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 细胞色素P450 27B1抗体（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CYP27B1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:细胞色素P450 27B1抗体
The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP27B1, a 508-amino acid protein that belongs to the XXVIIB subfamily of the cytochrome P450 family, localizes to the mitochondrion and is expressed in the kidney. The CYP27B1 protein catalyzes the conversion of 25-hydroxyvitamin D3 (25(OH)D) to 1-alpha,25-dihydroxyvitamin D3 (1,25(OH)2D) and functions in calcium metabolism, normal bone growth, and tissue differentiation. Mutations in the gene which encodes for CYP27B1 cause vitamin D-dependent rickets type 1 (VDDR-1), also designated pseudovitamin D deficiency rickets (PDDR), an autosomal recessive disease characterized by early onset of rickets with hypocalcemia and muscle weakness.
Function:
Catalyzes the conversion of 25-hydroxyvitamin D3 (25(OH)D) to 1-alpha,25-dihydroxyvitamin D3 (1,25(OH)2D) plays an important role in normal bone growth, calcium metabolism, and tissue differentiation.
细胞色素P450 27B1抗体
hze-0437P Streptavidin/HRP 辣根过氧化物酶标记链霉亲和素
hze-0362P Protein A/HRP 辣根过氧化物酶标记的蛋白A
hze-0292P BSA/HRP 辣根过氧化物酶标记牛血清白蛋白
hze-0361P rec Protein G/HRP 辣根过氧化物酶标记的重组蛋白G
hz-0855P-HRP Insulin/HRP 辣根过氧化物酶标记人胰岛素蛋白
hz-0311P-AP Biotin/AP 碱性磷酸酶标记生物素
hz-0312P-AP Avidin/AP 碱性磷酸酶标记亲合素
hz-0437P-AP Streptavidin/AP 碱性磷酸酶标记链霉亲和素
hz-0360G-AP Goat Anti-human IgA/AP 碱性磷酸酶标记羊抗人IgA
hz-0360R-AP Rabbit Anti-human IgA/AP 碱性磷酸酶标记兔抗人IgA
hz-0362P-AP Protein A/AP 碱性磷酸酶标记的蛋白A
hz-0292P-AP BSA/AP 碱性磷酸酶标记标记牛血清白蛋白
hz-0361P-AP rec Protein G/AP 碱性磷酸酶标记的重组蛋白G
hzb-0360G Goat Anti-human IgA/Biotin 生物素化羊抗人IgA
hza-0297R Rabbit Anti-human IgG/Streptavidin 链霉亲和素标记兔抗人IgG
hzb-0295P Rabbit IgG/Biotin 生物素化兔IgG
hzb-0297P human IgG/Biotin 生物素化人IgG
hzb-0296P mouse IgG/Biotin 生物素化小鼠IgG
hzF-0292P BSA/FITC 荧光素标记牛血清白蛋白
hzF-0366R Rb Anti-FITC/FITC 荧光素标记兔抗FITC
hzF-0360G Goat Anti-human IgA/FITC 荧光素标记羊抗人IgA
hzR-0292P BSA/RBITC 罗丹明标记牛血清白蛋白
hzR-0437P Streptavidin/RBITC 红色荧光素罗丹明标记链霉亲和素
hzR-0295P Rabbit IgG/RBITC 罗丹明标记兔IgG(细胞流式同型对照)
hzR-0296P Mouse IgG/RBITC 罗丹明标记小鼠IgG(细胞流式同型对照)
hzR-0294P Goat IgG/RBITC 罗丹明标记羊IgG(细胞流式同型对照)
hzR-0293P Rat IgG/RBITC 罗丹明标记大鼠IgG(细胞流式同型对照)
hzF-0312P Avidin/FITC 荧光素标记亲合素
hzF-0437P Streptavidin/FITC 荧光素标记链霉亲和素
hzF-0361P rec Protein G/FITC 荧光素标记重组纯化蛋白G
hzF-0362P Protein A/FITC FITC标记重组金黄色葡萄球菌蛋白A
hzR-0366R Rb Anti-FITC/RBITC 罗丹明标记兔抗FITC
hzR-0360G Goat Anti-human IgA/RBITC 罗丹明标记羊抗人IgA
hzR-0312P Avidin/RBITC 罗丹明标记亲合素
hzR-0362P Protein A/RBITC 罗丹明标记蛋白A
hzR-0326P Bovine IgG/RBITC 罗丹明标记牛IgG
hzR-0327P Bovine IgM/RBITC 罗丹明标记牛IgM
hzR-0310P Chicken IgG/RBITC 罗丹明标记鸡IgG
