XVII型胶原蛋白/胶原蛋白17/17型胶原蛋白抗体

英文名称    Collagen XVII    

中文名称    XVII型胶原蛋白/胶原蛋白17/17型胶原蛋白抗体    

别    名    180 kDa bullous pemphigoid antigen 2; Alpha 1 type XVII collagen; BA16H23.2; BP 180; BP180; BPAG 2; BPAG2; Bullous pemphigoid antigen 2; COL17A1; Collagen 17; Collagen alpha 1 XVII chain; Collagen alpha 1(XVII) chain; Collagen alpha1 XVII chain; Collagen type XVII alpha 1; Collagen XVII alpha 1 polypeptide; CollagenXVII; Epidermolysis bullosa junctional localisata variant; FLJ60881; KIAA0204; LAD 1; LAD.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  信号转导      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 XVII型胶原蛋白/胶原蛋白17/17型胶原蛋白抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    150kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Collagen XVII    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

XVII型胶原蛋白/胶原蛋白17/17型胶原蛋白抗体产品介绍    background:

This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008]

Function:
Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in the gene coding for collagen XVII are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD 1, is generated by proteolytic processing of the full length form. Two transcript variants, one resulting from alternative splicing in the 3' UTR, have been identified for this gene.    

XVII型胶原蛋白/胶原蛋白17/17型胶原蛋白抗体

hz-5568R phospho-DNA PK/PRKDC(Ser2612)  磷酸化DNA依赖性蛋白激酶抗体

hz-0678R Dnmt1  DNA甲基转移酶1抗体

hz-5844R SMAGP  小细胞跨膜糖化蛋白抗体

hz-5294R phospho-Dnmt1(Ser154)  磷酸化DNA甲基转移酶1抗体

hz-5295R phospho-Dnmt1(Ser732)  磷酸化DNA甲基转移酶1抗体

hz-5296R phospho-Dnmt1(Tyr399)  磷酸化DNA甲基转移酶1抗体

hz-5297R phospho-Dnmt1(Tyr969)  磷酸化DNA甲基转移酶1抗体

hz-0497R Dnmt3a  DNA甲基转移酶-3α抗体

hz-5845R TAG1/CNTN2  瞬时表达轴索糖蛋白1抗体

hz-5847R ADAM12/MLTN  去整合素样金属蛋白酶12抗体

hz-0301R Dnmt3 Beta  DNA甲基转移酶-3β抗体

hz-1359R DNAPK/PRKDC  DNA依赖蛋白激酶催化亚基抗体

hz-2102R DNPK1  DNA依赖蛋白激酶催化亚基抗体

hz-3794R DOG-1/TMhz16A  跨膜蛋白16A/钙激活氯离子通道抗体

hz-1467R DOK1  D酪氨酸激酶衰减蛋白1抗体

hz-5289R phospho-DOK1(Tyr362)  磷酸化D酪氨酸激酶衰减蛋白1抗体

hz-5290R phospho-DOK1 (Tyr398)  磷酸化D酪氨酸激酶衰减蛋白1抗体

hz-2746R DOK2  D酪氨酸激酶衰减蛋白2抗体

hz-3101R Phospho-p56Dok2(Tyr351)  磷酸化D酪氨酸激酶衰减蛋白2抗体

hz-3102R Phospho-p56Dok2(Tyr299)  磷酸化D酪氨酸激酶衰减蛋白2抗体

hz-3103R Phospho-p56Dok2(Tyr142)  磷酸化D酪氨酸激酶衰减蛋白2抗体

hz-5143R DP1/TFDP1  转录因子DP1抗体

hz-0597R DPPA2/PESCRG1  多能发育相关基因2抗体

hz-5848R ADAM15  去整合素样金属蛋白酶15抗体

hz-0421R DR3/APO3/TWEAK  死亡受体3抗体

hz-5849R ADAM18  去整合素样金属蛋白酶18抗体

hz-5850R ADAM19  去整合素样金属蛋白酶19抗体

hz-0591R TRAILR1/DR4/APO2  死亡受体4抗体

hz-5891R Periostin  成骨细胞特异性因子2抗体

hz-3785R DRAK2  DAP凋亡诱导蛋白激酶2抗体

hz-1696R TRAILR2/DR5/CD262  肿瘤细胞调亡素/死亡受体5抗体

hz-1561R DTNBP1  精神分裂症易感基因抗体

hz-5852R ADAM20  去整合素样金属蛋白酶20抗体

hz-3607R DRP3/Dystrobrevin alpha  肌营养蛋白α抗体