Cezanne蛋白抗体

英文名称    Cezanne    

中文名称    Cezanne蛋白抗体    

别    名    Cellular zinc finger anti NF kappa B protein; Cellular zinc finger anti-NF-kappa-B protein; CEZANNE; HGNC:16683; OTU domain containing protein 7B; OTU domain containing protein 7B; OTU domain-containing protein 7B; OTU7B_HUMAN; OTUD7B; ZA20D1; Zinc finger A20 domain containing protein 1; Zinc finger A20 domain-containing protein 1; Zinc finger protein Cezanne.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  信号转导  激酶和磷酸酶  表观遗传学  泛素      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Cow, Horse, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 Cezanne蛋白抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    92kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Cezanne    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 ∑C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20∑C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ∑C.    

Cezanne蛋白抗体产品介绍    background:

OTUD7B (OTU domain-containing protein 7B), also known as ZA20D1 or Cezanne, is an 843 amino acid protein that localizes to both the nucleus and the cytoplasm. Expressed in a variety of tissues, including liver, kidney, heart and immature B-cells, OTUD7B functions to hydrolyze branched and linear forms of polyubiquitin, specifically deubiquinating Lys-48- and Lys-63-linked polyubiquitin chains. Via its ability to deubiquinate target proteins, OTUD7B regulates the inflammatory response within the cell and may play a role in cell survival. More specifically, OTUD7B forms a negative feedback loop in pro-inflammatory signaling, thereby suppressing NFⅹB activity and helping to resolve inflammatory responses. OTUD7B contains one C-terminal A20-type zinc finger, one OTU domain and one N-terminal TRAF-binding domain through which it conveys its deubiquitinating activity.

Function:
Has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin. Negative regulator of nuclear factor NF-kappa-B.    

Cezanne蛋白抗体

hz-0308P-APhz Horse IgG/APC  荧光素APC标记马IgG

hz-0374P-APhz Horse IgM/APC  荧光素APC标记马IgM

hz-0297P-APhz human IgG/APC  荧光素APC标记人IgG

hz-0345P-APhz human IgM/APC  荧光素APC标记人IgM

hz-0360P-APhz human IgA/APC  荧光素APC标记人IgA

hz-0335P-APhz Monkey IgG/APC  荧光素APC标记猴IgG

hz-0336P-APhz Monkey IgM/APC  荧光素APC标记猴IgM

hz-0368P-APhz Mouse IgM/APC  荧光素APC标记小鼠IgM

hz-0309P-APhz pig IgG/APC  荧光素APC标记猪IgG

hz-0369P-APhz Rabbit IgM/APC  荧光素APC标记兔IgM

hz-0346P-APhz Rat IgM/APC  荧光素APC标记大鼠IgM

hz-0789P-APhz Insulin Protein /APC  荧光素APC标记猪胰岛素蛋白

hz-P0002-APhz KLH/APC  荧光素APC标记血蓝蛋白

hz-P0003-APhz OVA/APC  荧光素APC标记鸡卵白蛋白

hz-0945P-APhz HSA(Human sermu albumin)/APC  荧光素APC标记人血白蛋白

hz-2179P-APhz AACT/APC  荧光素APC标记胰糜蛋白酶

hz-0437P-hzy3 Streptavidin/Cy3  荧光素Cy3标记链霉亲和素

hz-0312P-hzy3 Avidin/Cy3  荧光素Cy3标记亲合素

hz-0362P-hzy3 Protein A/Cy3  Cy3标记蛋白A

hz-0295P-hzy3 Rabbit IgG/Cy3  荧光素Cy3标记兔IgG(细胞流式同型对照)

hz-0296P-hzy3 Mouse IgG/Cy3  荧光素Cy3标记小鼠IgG(细胞流式同型对照)

hz-0294P-hzy3 Goat IgG/Cy3  荧光素Cy3标记羊IgG(细胞流式同型对照)

hz-0293P-hzy3 Rat IgG/Cy3  荧光素Cy3标记大鼠IgG(细胞流式同型对照)

hz-0326P-hzy3 Bovine IgG/Cy3  荧光素Cy3标记牛IgG

hz-0327P-hzy3 Bovine IgM/Cy3  荧光素Cy3标记牛IgM

hz-0310P-hzy3 Chicken IgG/Cy3  荧光素Cy3标记鸡IgG

hz-0314P-hzy3 Chicken IgM/Cy3  荧光素Cy3标记鸡IgM

hz-0303P-hzy3 dog IgG/Cy3  荧光素Cy3标记狗IgG

hz-0373P-hzy3 dog IgM/Cy3  荧光素Cy3标记狗IgM

hz-0370P-hzy3 Goat IgM/Cy3  荧光素Cy3标记羊IgM

hz-0358P-hzy3 Guinea pig IgG/Cy3  荧光素Cy3标记豚鼠IgG

hz-0375P-hzy3 Guinea pig IgM/Cy3  荧光素Cy3标记豚鼠IgM

hz-0308P-hzy3 Horse IgG/Cy3  荧光素Cy3标记马IgG

hz-0374P-hzy3 Horse IgM/Cy3  荧光素Cy3标记马IgM

hz-0297P-hzy3 human IgG/Cy3  荧光素Cy3标记人IgG

hz-0345P-hzy3 human IgM/Cy3  荧光素Cy3标记人IgM