中心体蛋白CEP128抗体

英文名称    CEP164    

中文名称    中心体蛋白CEP128抗体    

别    名    AI450905; BC027092; CE164_HUMAN; Centrosomal protein of 164 kDa; Cep164; CEP164; D030051D21; FLJ54767; KIAA1052; MGC38792; mKIAA1052; OTTMUSP00000042044; RGD1560988; RGD1561243.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  信号转导  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 中心体蛋白CEP128抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    164kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CEP128    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

中心体蛋白CEP128抗体产品介绍    background:

This gene encodes a centrosomal protein involved in microtubule organization, DNA damage response, and chromosome segregation. The encoded protein is required for assembly of primary cilia and localizes to mature centrioles. Defects in this gene are a cause of nephronophthisis-related ciliopathies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

Function:
Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA,CHK2 and CHK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHK1.    

中心体蛋白CEP128抗体

hz-2090P P53(wt-p53)  肿瘤抑制基因抗原（野生型P53）

hz-0913P Mtp53(Mutant type p53)  突变型P53抗原

hz-0942P WIG-1(wtp53-induced gene 1)  野生型p53诱导基因1抗原

hz-1346P P73 protein  P73肿瘤抑制基因抗原

hz-1426P p70 S6 Kinase/P70 Beta1  p70S6Kb抗原

hz-0588P PALB2(partner and locaizer of BRCA2)  乳腺癌易感基因相关蛋白2

hz-1478P PAFR/PTAFR  血小板活化因子受体抗原

hz-2270P Phospho-PAK4 (Ser99) peptide  磷酸化p21激活激酶4多肽抗原

hz-0655P PAK7/PAK5/MBT  激活激酶PAK7/PAK5抗原

hz-0828P PAR-1 (Protease-activated receptors-1)  蛋白酶激活受体-1抗原

hz-1178P PAR-2 (Protease-activated receptors-2)  蛋白酶激活受体-2抗原

hz-1196P PAR4 (protease-activated receptor 4)  蛋白酶活化受体4/前列腺细胞凋亡反应蛋白4抗原

hz-2138P PARP(poly ADP-ribose polymerase)N-Terminus  多腺苷二磷酸多聚酶抗原(N端)

hz-1201P PAX8(Paired box gene 8)  配对盒基因8抗原

hz-1102P PAX9(Paired box gene 9)  配对盒基因9抗原

hz-1159P P-cadherin(placental)  P-钙粘附分子抗原

hz-1617P LI-cadherin(liver-intestine cadherin)  肝肠钙粘连蛋白抗原

hz-1608P PDCD4(programmed cell death 4)  凋亡相关蛋白4抗原

hz-1333P TFAR19(TF-1 cell apoptsis-related gene 19)  凋亡相关蛋白TFAR19抗原

hz-2215P PCNA(phosphos Dyr211)peptide  磷酸化增殖细胞核多肽抗原

hz-1345P PCX/PODXL(Podocalyxin)  足细胞特异蛋白抗原

hz-1316P PDGF-BB peptide  血小板源性生长因子-BB抗原

hz-0923P Pdx1(pancreatic and duodenal homeobox 1)  胰十二指肠同源异型盒基因抗原

hz-2219P pectinesterase inhibitor 18 peptide  果胶酶抗原

hz-1084P PEG10(Paternally expressed gene 10)  肝癌高表达基因抗原

hz-2106P PENK/Enkephalin A(Preproencephalin A)  脑啡肽

hz-0584P PEPT2 (Peptide-transporters 2)  肠道肽转运蛋白2/小肽转运蛋白2抗原

hz-2469P PERK(PRKR-like endoplasmic reticulum kinase)  蛋白激酶R样内质网激酶抗原

hz-0796P FSCN1 (Fascin 1 protein; fascin homolog 1, actin-bundling protein)  纤维束蛋白同源物1/肌动蛋白集束蛋白/圆线虫紫癜 抗原

hz-0563P P-GP(P-glycoprotein)  P-糖蛋白抗原

hz-1551P Pepsinogen C peptide  胃蛋白酶原C蛋白抗原

hz-1832P PGC-1 Alpha(peroxisome proliferator-activated receptor- Gamma coactivator 1 Alpha)  过氧化物酶体增殖物激活受体γ辅激活子1α抗原

hz-0823P PGRN (progranulin)  颗粒蛋白前体抗原

hz-1449P PHB(Prohibitin)  抑制素/肿瘤抑制因子抗原