胞吞再循环相关衔接蛋白CENTB1抗体

英文名称    CENTB1    

中文名称    胞吞再循环相关衔接蛋白CENTB1抗体    

别    名    ACAP 1; ACAP1; ACAP1_HUMAN; ANK repeat and PH domain-containing protein 1; Arf GAP with coiled coil ANK repeat and PH domains 1; Arf GAP with coiled coil, ankyrin repeat, and pleckstrin homology domains 1; Arf-GAP with coiled-coil; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1; ArfGAP with coiled-coil, ankyrin repeat and PH domains 1; CENT B1; Centaurin beta 1; Centaurin-beta-1; CENTB 1; Cnt b1; Cnt-b1; Cntb1; KIAA0050.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  信号转导  细胞粘附分子      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Horse, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 胞吞再循环相关衔接蛋白CENTB1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    81kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CENTB1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

胞吞再循环相关衔接蛋白CENTB1抗体产品介绍    background:

ACAP1 is a member of the ADP ribosylation factor family of ARF6 GTPase-activating proteins (GAP). GAPs are important regulators of Arf function by controlling the return of ARF to its inactive state. ACAP1 is related to AGAP1 and ASAP1, and all three proteins are similarly expressed in fibroblast cells such as NIH/3T3. Internalization and recycling of integrin receptors is important in cell adhesion and migration modulation, and once inside a cell, proteins and membranes are transported to the endosome where they are sorted for recycling or degradation. ACAP1 promotes cargo sorting by associating directly to recycling cargo proteins. Preventing this interaction inhibits protein recycling. ACAP1 binds transferrin receptors, promoting their transport to the plasma membrane from the endosome. Akt induced phosphorylation of ACAP1 at Ser 554 regulates ACAP1 interaction to integrin in endosomes, and downregulation of Akt or ACAP1 may inhibit cell migration on Fibronectin.

Function:
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface.    

胞吞再循环相关衔接蛋白CENTB1抗体

hz-2585P FOXF1(Forkhead box protein F1)  叉头蛋白F1抗原

hz-1775P FOXJ1/HFH-4 peptide  插头蛋白J1抗原

hz-1275P FoxP1(Forkhead box P1)  FoxP1（T细胞转录因子）抗原

hz-2687P FOXM1/HFH 11 peptide  插头蛋白M1抗原

hz-0886P Measles virus of fusion protein  麻疹病毒抗原（麻疹病毒融合蛋白）

hz-0895P FSH-R(Follicle-stimulating hormone receptor precursor)  促卵泡刺激素受体抗原

hz-1536P FSH(Follicle-stimulating hormone precursor)  促卵泡刺激素抗原

hz-1232P GABRA1(gamma-aminobutyric acid (GABA) A receptor, alpha 1)  γ1氨基丁酸A型受体α1抗原

hz-0533P GABAB1(GABAb Receptor 1)  g-氨基丁酸B1受体(多肽)

hz-1293P GABABR2/GB2(GABA B Receptor 2)  γ1氨基丁酸A型受体B2抗原

hz-1302P GAD-67 (glutamate decarboxylase 67)  谷氨酸脱羧酶-67抗原

hz-1361P GADD153(Growth arrest and DNA damage-inducible 153)  生长抑制DNA损伤基因153抗原

hz-1641P phospho GAP-43(pSer41)(phospho Growth associated protein 43 )  磷酸化神经生长相关蛋白43抗原

hz-0834P GAPDH  3-磷酸甘油醛脱氢酶(人)抗原

hz-2209P CXCR3/CD183 peptide  细胞表面趋化因子受体3抗原

hz-1452P GATA-3(GATA binding factor 3)  GATA结合蛋白3抗原

hz-1778P GATA-4(GATA binding factor 4)  GATA结合蛋白4抗原

hz-1250P Gax(growth arrest-specific homeobox)  生长终止特异性同源盒基因抗原

hz-1288P GDF8/MSTN(growth differntiation factor 8)  生长分化因子8抗原

hz-1024P GDNF (Glial cell line-derived neurotrphic factor)  胶质细胞源性神经营养因子抗原

hz-1160P Gelsolin  凝溶胶蛋白抗原

hz-0844P GFP  绿色荧光蛋白

hz-0890P GFP  绿色荧光蛋白

hz-1173P GITR (glucocorticoidinduced tumor necrosis factor receptor)  糖皮质激素诱导肿瘤坏死因子受体抗原

hz-1206P GLI1(GLI-Kruppel family mhzber 1)  下游转录因子Gli1蛋白抗原

hz-0933P GLP-1/KG-31(Glucagon-like peptide-1) peptide  胰高血糖素样肽-1（多肽）

hz-0085P GLP-1 peptide  胰高血糖素样肽-1（多肽）

hz-1559P GLP-1R peptide  胰高血糖素样肽-1受体多肽

hz-1207P GLUT3(Glucose transporter 3)  葡萄糖转运蛋白3抗原

hz-0999P GM-CSF(Granulocyte-Macrophage Colony Stimulating Factors)  粒细胞-巨噬细胞克隆刺激因子抗原

hz-1226P GPA33(glycoprotein A33 transmhzbrane)  糖蛋白A33(跨膜)抗原

hz-2426P glypican 1  磷脂酰基醇蛋白聚糖-1抗原

hz-1112P GPC3(glypican 3; Intestinal protein OCI-5; GTR2-2; MXR7)  磷脂酰基醇蛋白聚糖-3(多肽)

hz-2159P Glypican 4(Glypican proteoglycan 4)  磷脂酰基醇蛋白聚糖-4抗原