C型凝集素结构域家族9成员A抗体

英文名称    CLEC9A    

中文名称    C型凝集素结构域家族9成员A抗体    

别    名    C type lectin domain family 9, member A; C-type lectin domain family 9 member A; CLC9A_HUMAN; CLEC9A; DNGR1; HEEE9341; PRO34046; UNQ9341.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  信号转导  干细胞  糖蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 C型凝集素结构域家族9成员A抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    27kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CLEC9A    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

C型凝集素结构域家族9成员A抗体产品介绍    background:

The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-9A (C-type lectin domain family 9 member A), also known as DNGR1 (dendritic cell natural killer lectin group receptor 1), is a 241 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Expressed in myeloid lineage cells, brain, spleen and thymus, CLEC-9A is a group V C-type lectin-like receptor (CTLR) that acts as an activation receptor. The gene encoding CLEC-9A maps to human chromosome 12p13.2 and mouse chromosome 6 F3.

Function:
Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.    

C型凝集素结构域家族9成员A抗体

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hz-3640R Plectin  网蛋白抗体

hz-0281R PLGF/PIGF (human)  胎盘生长相关抗体（人）

hz-0280R PLGF/PIGF (mouse, rat, pig)  胎盘生长因子抗体（小鼠、大鼠、猪）

hz-0234R PLGF  胎盘生长因子抗体

hz-3535R PLK1  丝氨酸/苏氨酸蛋白激酶Plk1抗体

hz-3344R Phospho-PLK1(Thr210)  磷酸化丝/苏氨酸蛋白激酶Plk1抗体

hz-3345R Phospho-PLK1 (Ser137)  磷酸化丝/苏氨酸蛋白激酶Plk1抗体

hz-5588R Phospho-PLK1(Ser482+Ser486+Ser490)  磷酸化丝/苏氨酸蛋白激酶Plk1抗体

hz-3698R PML/TRIM19  早幼粒细胞白血病蛋白抗体

hz-0235R PMP22  外周髓鞘蛋白-22抗体

hz-1362R PMS2  肿瘤错配修复基因PMS2抗体

hz-2798R PNAT/NAT2  N-乙酰基转移酶2抗体

hz-3542R PNK1/PNKP  多聚合苷酸激酶3磷酸化酶抗体

hz-3355R Phospho-PNK1 (Ser114/Thr118)  磷酸化多聚合苷酸激酶3磷酸化酶抗体

hz-3912R PNMT  苯乙醇胺甲基转移酶抗体

hz-5108R PNPO  磷酸吡哆醇氧化酶抗体

hz-1048R Podoplanin Protein/gp36  平足蛋白抗体(淋巴管内皮细胞蛋白)

hz-0891R Pokhzon  扑克蒙蛋白抗体

hz-2157R Polycystin 1  多囊肾蛋白1抗体

hz-2158R Polycystin 2  多囊肾蛋白2抗体

hz-5107R PON1  芳香酯酶1(对氧磷酶)抗体

hz-0133M PP-1B  蛋白磷酸酯酶-1B抗体

hz-3756R PP1A/PP2CA/PPP1CA  蛋白磷酸酶2Cα抗体

hz-3740R phospho-PP1A/PP2CA (Thr320)  磷酸化蛋白磷酸酶2Cα抗体

hz-5422R PP1C gamma  蛋白磷酸酶γ1抗体

hz-0029R PP2A alpha/beta  蛋白质磷酸酶-2A抗体

hz-4162R PP2CA/PPM1A  蛋白磷酸酶2C亚型α抗体

hz-5586R phospho-PPM1A(Ser375)  磷酸化蛋白磷酸酶2C亚型α抗体

hz-0490R PP2Ac/PP4C  磷酸酯酶-2Ac抗体

hz-0250R PPAR-delta/beta  D型-过氧化酶活化增生受体抗体

hz-3614R PPAR alpha  α型-过氧化酶活化增生受体抗体

hz-4055R phospho-PPAR alpha(Ser12)  磷酸化α型-过氧化酶活化增生受体抗体

hz-0530R PPAR gamma  过氧化酶活化增生受体γ抗体