精子尾部结构蛋白抗体

英文名称    Cenexin1    

中文名称    精子尾部结构蛋白抗体    

别    名    Cenexin1/ODF2; sperm tail structural protein; 84 kDa outer dense fiber protein; Cenexin 1; Cenexin1 variant 1; KKT 4; KKT4; ODF 2; ODF 84; ODF2; ODF2/1; ODF2/2; ODF84; Outer dense fiber of sperm tail 2; Outer dense fiber of sperm tails 2; outer dense fiber of sperm tails; Outer dense fiber of sperm tails protein 2; Outer dense fiber of sperm tails, 84 kD; Outer dense fiber protein 2; Sperm outer dense fiber major protein 2; Testis specific autoantigen; ODFP2_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    免疫学  发育生物学  信号转导      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 精子尾部结构蛋白抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Cenexin1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

精子尾部结构蛋白抗体产品介绍    background:

Cenexin1 is an isoform of ODF2, that unlike ODF2 is present in several somatic cell types. Cenexin1 acts as a general scaffold protein that is specifically localised to the distal/subdistal appendages of mother centrioles. Cenexin1 is required for proper localization of Plk1 to the centrosomes. This centrosomal localization of Plk1 is required for proper microtubule function. Cenexin1 recruits Plk1 via a C-terminal extension of cenexin1 that is not present in ODF2. Cenexin1 is required for proper mitotic progression; depletion of Cenexin1 ultimately leads to chromosome missegregation and apoptosis. The ODF2 (outer dense fiber 2) gene encodes both ODF2 and Cenexin1, which have very different functions. ODF2 is a major component of sperm tail outer dense fibers (ODFs). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. They may help to maintain the passive elastic structures and elastic recoil of the sperm tail, and may also modulate sperm motility.

Function:
Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.    

精子尾部结构蛋白抗体

hz-6711R Netrin 4  轴突生长诱向因子4抗体

hz-6712R PAX4  配对盒同源基因4抗体

hz-6713R Laminin 5  层粘连蛋白5(laminin γ2)抗体

hz-6714R UGCGL2  二磷酸葡萄糖神经酰胺葡萄糖基转移酶2抗体

hz-6715R UGDH/UDPGDH  尿苷二磷酸葡萄糖脱氢酶抗体

hz-6716R Uricase  尿酸酶

hz-6717R NALP2/PAN1/PYPAF2  富含亮氨酸重复结构域蛋白2抗体

hz-6718R Dystrophin/DMD  肌营养不良蛋白

hz-6719R LGI1/ETL1  富含亮氨酸胶质瘤失活蛋白1抗体

hz-6720R GANAB/alpha Glucosidase II  α葡萄糖苷酶2抗体

hz-6721R NLG1/KIRREL2  肾病样蛋白1抗体

hz-6722R MAPK organizer 1/Morg1  丝裂原活化蛋白激酶组织蛋白1抗体

hz-6723R PNPLA6/NTE  含patatin样磷脂酶6抗体

hz-6724R OTC  鸟氨酸氨基甲酰转移酶抗体

hz-6725R Desmoglein 1/DSG1  桥粒芯糖蛋白1

hz-6727R CAMKIV/CAMK4  钙/钙调蛋白依赖性蛋白激酶4抗体

hz-6728R phospho-CAMK4(Thr196 + Thr200)  磷酸化钙/钙调蛋白依赖性蛋白激酶4抗体

hz-6730R LBP1/Upstream Binding Protein 1  上游结合蛋白1抗体

hz-6732R SDF4  基质细胞衍生因子4抗体（钙结合蛋白）

hz-6733R SECTM1  分泌和跨膜蛋白1抗体

hz-6734R SERBP1  纤溶酶原激活物抑制剂1 RNA结合蛋白抗体

hz-6735R SFR19  剪接因子，精氨酸/丝氨酸丰富19

hz-6736R SOX11  转录因子SOX-11蛋白抗体

hz-6737R SVH/ARMC10  肝癌蛋白剪接变异体蛋白抗体

hz-6738R THRSP  甲状腺激素反应蛋白抗体

hz-6739R TIMM17A  线粒体内膜转位酶抗体

hz-6740R TMhz49  跨膜蛋白49抗体

hz-6741R TMS1/ASC  凋亡相关斑点样蛋白ASC抗体

hz-6742R TPD52/Prostate and colon associated protein  前列腺癌和结肠癌相关蛋白

hz-6743R TPD54/TPD52L2  肿瘤蛋白D54蛋白抗体

hz-6744R TRIM47  星形细胞瘤高表达蛋白抗体（环指蛋白100）

hz-6745R TSP50  肿瘤/睾丸抗原20抗体

hz-6746R TULP2/CT65/Cancer testis antigen 65  肿瘤/睾丸抗原65

hz-6747R TERT/EST2/Telomerase reverse transcriptase  端粒酶相关蛋白2抗体（端粒酶逆转录酶）