碳水化合物激酶结构域蛋白质抗体

英文名称    CARKD    

中文名称    碳水化合物激酶结构域蛋白质抗体    

别    名    Carbohydrate kinase domain containing; carbohydrate kinase domain-containing protein; FLJ10769; LP3298; NNRD_HUMAN.    

说 明 书    0.2ml      

研究领域    细胞生物  免疫学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）碳水化合物激酶结构域蛋白质抗体 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    37kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CARKD    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

碳水化合物激酶结构域蛋白质抗体产品介绍    background:

CARKD is a 347 amino acid protein that belongs to the YjeF family and exists as three alternatively spliced isoforms. Containing one YjeF C-terminal domain, CARKD is encoded by a gene that maps to human chromosome 13q34. Chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

Function:
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).     

碳水化合物激酶结构域蛋白质抗体

hz-9516R ALAS2/ALAS-E  5-氨基乙酰丙酸合酶1抗体

hz-9517R AMPD3  红细胞腺苷脱氨酶3抗体

hz-9518R AHSP/ERAF  α红细胞分化相关因子抗体

hz-9519R BPGM  红细胞2,3 - 二磷酸甘油酸合成酶抗体

hz-9520R DYRK3  双特异性酪氨酸磷酸化调节激酶3抗体

hz-5558R phospho-PTPN7(Ser93)  磷酸化非受体型蛋白酪氨酸磷酸酶7抗体

hz-9521R FECH/Ferrochelatase  铁螯合酶抗体

hz-9522R MPP1/hzP55  红细胞膜蛋白55抗体

hz-9523R Mitoferrin 1  线粒体铁转运蛋白1抗体

hz-9524R PIGA  红细胞磷脂酰肌醇聚糖A抗体

hz-9525R Factor H  补体因子H抗体

hz-9526R EKLF/KLF1, 2, 4  上皮锌指蛋白1, 2, 4抗体

hz-9527R ALAS1/ALAS-H  5-氨基乙酰丙酸合酶1抗体

hz-9529R C6orf64  6号染色体开放阅读框64抗体

hz-9530R C6orf192  8号染色体开放阅读框192抗体

hz-9531R TSBP  睾丸特异蛋白抗体

hz-9532R AKD1  腺苷酸激酶结构域蛋白1抗体

hz-9533R C6orf1  6号染色体开放阅读框1抗体

hz-9534R C6orf120  6号染色体开放阅读框120抗体

hz-9535R α-TAT  α微管蛋白乙酰转移酶1抗体

hz-9537R C6orf150  6号染色体开放阅读框150抗体

hz-9538R C6orf174  6号染色体开放阅读框174抗体

hz-9540R C6orf58  6号染色体开放阅读框58抗体

hz-9541R Orai2  跨膜蛋白Orai2抗体

hz-9542R BAAT1/C7orf27  7号染色体开放阅读框27抗体

hz-9543R CCZ1  CCZ1蛋白抗体

hz-9544R MMS21/NSE2  E3连接酶MMS21蛋白抗体

hz-9545R C9orf86  9号染色体开放阅读框86抗体

hz-9546R FIBCD1  含纤维蛋白原C结构域蛋白1抗体

hz-9547R PGGT1A/FNTA  蛋白香叶烯基转移酶1α抗体

hz-9548R PGGT1B/FNTB  蛋白香叶烯基转移酶1β（FTβ）抗体

hz-9549R FRG2B  FRG2B蛋白抗体

hz-9550R CXorf56  X染色体开放阅读框56抗体

hz-9551R BEND2/CXorf56  BEND2蛋白抗体

hz-9552R CXorf21  X染色体开放阅读框21抗体