含半胱氨酸和组氨酸丰富域蛋白1抗体

英文名称    CHORDC1    

中文名称    含半胱氨酸和组氨酸丰富域蛋白1抗体    

别    名    CHORD containing protein 1; Chord domain containing protein 1; CHORD domain-containing protein 1; CHORD-containing protein 1; CHORDC1; CHP-1; CHP1; CHRD1_HUMAN; Cysteine and histidine rich domain (CHORD) containing 1; Cysteine and histidine rich domain (CHORD) containing, zinc binding protein 1; Cysteine and histidine rich domain containing 1; Cysteine and histidine rich domain containing zinc binding protein 1; Cysteine and histidine-rich domain-containing protein 1; FLJ37289; Protein morgana.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  免疫学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 含半胱氨酸和组氨酸丰富域蛋白1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    37kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CHORDC1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

含半胱氨酸和组氨酸丰富域蛋白1抗体产品介绍    background:

Human CHP1 and the C. elegans homolog Chp are CHORD domain-containing proteins that are largely related, and their corresponding genes are evolutionarily conserved among various eukaryotic organisms (1,2). The unique CHORD domain is characterized as 60 amino acids in length, and contains six highly conserved cysteine residues, two histidine residues and a distinct Zn2+-binding domain (3). CHP1 and the other metazoan orthologs have tandem CHORD domains that are located at both the N- and C- termini (1,4). These proteins are implicated in germline development and embryogenesis as mutations affecting the CHORD domain of the nematode protein Chp result in semisterility and embryonic lethality (1,5).

Function:
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis.    

含半胱氨酸和组氨酸丰富域蛋白1抗体

hz-2095P Integrin alpha 1  整合素α1抗原

hz-1051P Integrin Alpha4 Beta7/LPAM-1 (Lymphocyte Peyer’s patch Adhesion Molecule 1/Integrin alpha4,beta7)  整合素α4β7抗原

hz-1274P Integrin AlphaE2/CD103  整合素αE2抗原

hz-1568P ENPP3/CD203c(ectonucleotide pyrophosphatase/phosphodiesterase 3)  ENPP3抗原

hz-1109P IQGAP1  支架蛋白抗原

hz-1404P IRF-1(Interferon regulatory factor-1)  干扰素调节因子抗原

hz-1427P IRAK 2  白介素-1受体相关激酶2

hz-2216P IL-1RA (Interleukin-1 receptor antagonist)peptide  白介素-1受体拮抗剂抗原

hz-1816P Integrin a7(integrin alpha 7)  整合素α7抗原

hz-0486P integrin Beta1(ITG- Beta1/CD29)  粘附分子整合素β1抗原

hz-0567P Integrin Alpha5(ITG- AlphaV/CD49e)  粘附分子整合素α5抗原

hz-2250P Integrin alpha V/CD51 peptide  整合素αV抗原

hz-1439P JAK1(Tyrosine-protein kinase JAK1; Janus kinase 1)  蛋白质酪氨酸激酶JAK-1抗原

hz-0908P JAK2(Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2)  蛋白质酪氨酸激酶JAK-2抗原

hz-2485P phospho JAK2(phospho-Tyr1007+Tyr1008)  磷酸化蛋白酪氨酸激酶JAK-2抗原

hz-0501P JNK1/3 (c-Jun amino-terminal kinase 1/3)  c-Jun氨基末端激酶1/3多肽抗原

hz-1640P phospho-JNK1/2/3(pThr183/pTyr185) peptide  磷酸化氨基末端激酶1/2/3（pJNK1/2/3）抗原

hz-2130P Ki-67(Antigen identified by monoclonal antibody Ki 67)  Ki-67 Antigen

hz-1064P Klf4 (Kruppel likefactor 4)  肠道内富含的Kruppel样因子抗原

hz-2019P phospho-KLF5/Krueppel-like factor 5 (pSer272)  磷酸化肠道内富含的Kruppel样因子5抗原

hz-2020P phospho-Klf5/CKLF/Kruppel like factor 5, Human, mo, rat, horse, bovine, rabbit, pig, dog  磷酸化肠道内富含的Kruppel样因子5抗原

hz-1810P LDH(Lactate Dhzydrogenase)  乳酸脱氢酶抗原

hz-0961P Leptin receptor  瘦素受体

hz-1451P PAFAH2/Lp-PLA2/PLA2G7(platelet-activating factor acetylhydrolase 2)  脂蛋白磷脂酶A2抗原

hz-1117P Lgr5/GPR49  肠上皮干细胞蛋白（多肽）

hz-0951P LH(Luteinizing Hormone)  促黄体生成素抗原

hz-0952P LH(Luteinizing Hormone)  人促黄体生成素(多肽)

hz-0984P LH/CG Receptor(Luteinizing Hormone/Choriogonadotropin Receptor)  人促黄体生成素受体抗原

hz-1054P L-HDC (L-Histidine decarboxylase)  L-组氨酸脱羧酶抗原

hz-1058P LIF peptide  白血病抑制因子抗原

hz-1458P LIFR/CD118 peptide  白血病抑制因子受体抗原

hz-1177P Lingo-1  Nogo受体作用蛋白抗原

hz-2035P LIS1(Lissencephaly-1 protein)  无脑回的致病基因LIS1抗原

hz-0824P LFABP/FABP-1(Liver Fatty acid binding protein)  肝脏型脂肪酸结合蛋白抗原

hz-0897P LFABP/FABP-2(Liver Fatty acid binding protein)  肝脏型脂肪酸结合蛋白抗原