细胞周期通道和神经细胞分化蛋白1抗体

英文名称    CEND1    

中文名称    细胞周期通道和神经细胞分化蛋白1抗体    

别    名    BM88; BM88 antigen; Cell cycle exit and neuronal differentiation 1; Cell cycle exit and neuronal differentiation protein 1; FLJ90066; MGC34326; CEND_HUMAN    

说 明 书    0.2ml      

研究领域    细胞生物  神经生物学  细胞周期蛋白  细胞分化  细胞类型标志物      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Horse,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 细胞周期通道和神经细胞分化蛋白1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    15kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CEND1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

细胞周期通道和神经细胞分化蛋白1抗体产品介绍    background:

BM88 is a 149 amino acid protein that belongs to the CEND1 familly. Involved in neuroblastoma cell differentiation, BM88 is a single-pass type IV membrane protein that is neuron specific. It is suggested that BM88 forms a dimer of two identical polypeptides linked by disulfide bridges. BM88 has a central proline-rich region containing four PxxP motifs, which typically bind SRC homology-3 (SH3) domains, as well as a putative C-terminal transmembrane region, and several potential sites for N-glycosylation, myristoylation and phosphorylation. It is also suggested that a novel signaling mechanism exists by which BM88 interferes with calcium release from inositol 1,4,5-trisphosphate-sensitive stores and exerts anti-proliferative and anti-apoptotic functions. BM88 is an important molecular target for HDAC inhibition, and transcription of BM88 is induced by trichostatin-A.

Function:
CEND1 is a neuron-specific protein. The similar protein in pig enhances neuroblastoma cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Multiple pseudogenes have been reported for this gene.    

细胞周期通道和神经细胞分化蛋白1抗体

hz-0370R-hzy5.5 Rabbit Anti-Goat IgM/Cy5.5  Cy5.5标记的兔抗羊IgM

hz-0370R-hzy7 Rabbit Anti-Goat IgM/Cy7  Cy7标记的兔抗羊IgM

hz-0370R-PE Rabbit Anti-Goat IgM/PE  PE标记的兔抗羊IgM

hz-0370R-PE-hzy3 Rabbit Anti-Goat IgM/PE-Cy3  PE-Cy3标记的兔抗羊IgM

hz-0370R-PE-hzY5 Rabbit Anti-Goat IgM/PE-CY5  PE-CY5标记的兔抗羊IgM

hz-0370R-APhz Rabbit Anti-Goat IgM/APC  APC标记的兔抗羊IgM

hz-0370R-AF350 Rabbit Anti-Goat IgM/Alexa Fluor 350  Alexa Fluor 350标记的兔抗羊IgM

hz-0370R-AF488 Rabbit Anti-Goat IgM/Alexa Fluor 488  Alexa Fluor 488标记的兔抗羊IgM

hz-0370R-AF555 Rabbit Anti-Goat IgM/Alexa Fluor 555  Alexa Fluor 555标记的兔抗羊IgM

hz-0370R-AF647 Rabbit Anti-Goat IgM/Alexa Fluor 647  Alexa Fluor 647标记的兔抗羊IgM

hz-0370R-PE-hzy5.5 Rabbit Anti-Goat IgM/PE-Cy5.5  PE-Cy5.5标记的兔抗羊IgM

hz-0370R-PE-hzy7 Rabbit Anti-Goat IgM/PE-Cy7  PE-Cy7标记的兔抗羊IgM

hz-0370R-RBIThz Rabbit Anti-Goat IgM/RBITC  罗丹明标记的兔抗羊IgM

hz-0370R-FIThz Rabbit Anti-Goat IgM/FITC  FITC标记的兔抗羊IgM

hz-0358R-FIThz Rabbit Anti-Guinea pig IgG/FITC  FITC标记的兔抗豚鼠IgG

hz-0358R-AF555 Rabbit Anti-Guinea pig IgG/Alexa Fluor 555  Alexa Fluor 555标记的兔抗豚鼠IgG

hz-0358R-AF647 Rabbit Anti-Guinea pig IgG/Alexa Fluor 647  Alexa Fluor 647标记的兔抗豚鼠IgG

hz-0358R-PE-hzy5.5 Rabbit Anti-Guinea pig IgG/PE-Cy5.5  PE-Cy5.5标记的兔抗豚鼠IgG

hz-0358R-PE-hzy7 Rabbit Anti-Guinea pig IgG/PE-Cy7  PE-Cy7标记的兔抗豚鼠IgG

hz-0358R-RBIThz Rabbit Anti-Guinea pig IgG/RBITC  罗丹明标记的兔抗豚鼠IgG

hz-0358R-hzy3 Rabbit Anti-Guinea pig IgG/Cy3  Cy3标记的兔抗豚鼠IgG

hz-0358R-hzy5 Rabbit Anti-Guinea pig IgG/Cy5  Cy5标记的兔抗豚鼠IgG

hz-0358R-hzy5.5 Rabbit Anti-Guinea pig IgG/Cy5.5  Cy5.5标记的兔抗豚鼠IgG

hz-0358R-hzy7 Rabbit Anti-Guinea pig IgG/Cy7  Cy7标记的兔抗豚鼠IgG

hz-0358R-PE Rabbit Anti-Guinea pig IgG/PE  PE标记的兔抗豚鼠IgG

hz-0358R-PE-hzy3 Rabbit Anti-Guinea pig IgG/PE-Cy3  PE-Cy3标记的兔抗豚鼠IgG

hz-0358R-PE-hzY5 Rabbit Anti-Guinea pig IgG/PE-CY5  PE-CY5标记的兔抗豚鼠IgG

hz-0358R-APhz Rabbit Anti-Guinea pig IgG/APC  APC标记的兔抗豚鼠IgG

hz-0358R-AF350 Rabbit Anti-Guinea pig IgG/Alexa Fluor 350  Alexa Fluor 350标记的兔抗豚鼠IgG

hz-0358R-AF488 Rabbit Anti-Guinea pig IgG/Alexa Fluor 488  Alexa Fluor 488标记的兔抗豚鼠IgG

hz-0358R-AP Rabbit Anti-Guinea pig IgG/AP  碱性磷酸酶（AP）标记的兔抗豚鼠IgG

hz-0358R-HRP Rabbit Anti-Guinea pig IgG/HRP  辣根过氧化物酶标记的兔抗豚鼠IgG

hz-0358R-Gold Rabbit Anti-Guinea pig IgG/Gold  胶体金标记的兔抗豚鼠IgG