盘状结构域受体蛋白2抗体

英文名称    CD167b/DDR2    

中文名称    盘状结构域受体蛋白2抗体    

别    名    DDR 2; DDR2; ; DDR 2; CD167b antigen; Cell migration inducing protein 20; Discoidin domain containing receptor 2; Discoidin domain receptor 2; Discoidin domain receptor family member 2v Hydroxyaryl protein kinase; MIG20a; Migration inducing gene 16 protein; Neurotrophic tyrosine kinase; Neurotrophic tyrosine kinase receptor related 3v NTRKR 3; NTRKR3v Receptor protein tyrosine kinase TKTv Receptor related 3; TKTv TYRO 10; TYRO10; Tyrosine kinase receptor related to neurotrophic TRK; Tyrosine protein kinase TYRO 10; Tyrosine protein kinase TYRO10; Tyrosylprotein kinase; DDR2_HUMAN; Discoidin domain-containing receptor 2; CD167 antigen-like family member B; Discoidin domain-containing receptor tyrosine kinase 2; Neurotrophic tyrosine kinase, receptor-related 3; Receptor protein-tyrosine kinase TKT; CD167b.    

说 明 书    0.1ml  0.2ml      

研究领域    心血管  神经生物学  通道蛋白  细胞膜受体      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 盘状结构域受体蛋白2抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    92kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CD167b    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

盘状结构域受体蛋白2抗体产品介绍    background:

Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].

Function:
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.    

盘状结构域受体蛋白2抗体

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hz-3154R Phospho-c-Fos (Thr325)  磷酸化c-fos抗体

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hz-4286R VAV3  鸟嘌呤核苷酸交换因子VAV3抗体

hz-0539R CGA/ Chromogranin A  嗜铬粒素A抗体

hz-5737R phospho-VAV3(Tyr173)  磷酸化鸟嘌呤核苷酸交换因子VAV3抗体

hz-5738R CKAP5/ch TOG  结肠和肝肿瘤高表达蛋白抗体

hz-0543R CGB  嗜铬粒素B抗体

hz-0791R CGRP/CGRP2  CGRP降钙素基因相关肽抗体

hz-5740R Cdc23  细胞分裂周期蛋白23抗体

hz-4287R AKIP  极光激酶A相互作用蛋白1抗体

hz-0042R ChAT  ChAT胆碱乙酰转移酶抗体

hz-3860R CHRDL2  乳腺肿瘤新因子1抗体

hz-1681R CHK1/CHEK1  细胞周期检测点激酶1抗体

hz-5250R phospho-CHEK1 (Ser280)  磷酸化细胞周期检测点激酶1抗体

hz-5251R phospho-CHEK1(Ser317)  磷酸化细胞周期检测点激酶1抗体

hz-2394R CKLF  趋化素样蛋白抗体

hz-5278R phospho-CHEK1 (Ser345)  磷酸化细胞周期检测点激酶1抗体

hz-1391R CHK2  细胞周期检测点激酶2抗体

hz-3721R Phospho-CHK2 (Thr68)  磷酸化细胞周期检测点激酶2抗体

hz-4000R Phospho-CHK2 (ser19)  磷酸化细胞周期检测点激酶2抗体

hz-5257R Phospho-CHK2 (ser516)  磷酸化细胞周期检测点激酶2抗体

hz-5260R Phospho-CHK2 (ser33)  磷酸化细胞周期检测点激酶2抗体

hz-5275R Phospho-CHK2 (Thr387)  磷酸化细胞周期检测点激酶2抗体

hz-0971R Chloramphenicol  氯霉素抗体

hz-2353R Mast Cell Chymase  肥大细胞类糜蛋白酶1抗体

hz-0972R Gentamicin  庆大霉素抗体

hz-0973R Tetracycline  四环素抗体

hzm-0972M Gentamicin(3G7)  庆大霉素单克隆抗体

hz-0974R Oxytetracycline  土霉素抗体

hz-2059R Metronidazole  甲硝唑抗体

hzm-2059M Metronidazole(1C2)  甲硝唑单克隆抗体

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