磷酸化细胞周期检测点激酶1抗体

英文名称    phospho-CHEK1 (Ser280)    

中文名称    磷酸化细胞周期检测点激酶1抗体    

别    名    Chk1 (Phospho-Ser280); CHEK1 (phospho Ser280); CHEK1 (phospho Ser280); p-CHEK1 (Ser280); Cell cycle checkpoint kinase; Checkpoint, S. pombe, homolog of, 1; Checkpoint kinase 1; Checkpoint kinase 1 homolog (S. pombe); CHEK 1; CHEK-1; CHEK1; Chk 1; Chk1; CHK1 checkpoint homolog (S. pombe); EC 2.7.11.1; rad27; Serine/threonine protein kinase Chk1; Serine/threonine-protein kinase CHK1; STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae); C85740; CHK1_HUMAN.    

说 明 书    0.1ml      

产品类型    磷酸化抗体     

研究领域    肿瘤  免疫学  染色质和核信号  信号转导  细胞周期蛋白  激酶和磷酸酶      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 磷酸化细胞周期检测点激酶1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    54kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated Synthesised phosphopeptide derived from mouse CHEK1 around the phosphorylation site of Ser280    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

磷酸化细胞周期检测点激酶1抗体产品介绍    background:

The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011].    

磷酸化细胞周期检测点激酶1抗体

hz-11223R ATRIP/TREX1  系统性红斑狼疮相关蛋白TREX1抗体

hz-11224R phospho-ATRIP (Ser68+Ser72)  系统性红斑狼疮先关蛋白TREX1抗体

hz-11225R Phospho-ATRIP (Ser224)  系统性红斑狼疮先关蛋白TREX1抗体

hz-11226R Phospho-CHEK1 (Ser296)  磷酸化细胞周期检测点激酶1抗体

hz-11227R Microcephalin 1/BRIT1  小脑症基因1/认知相关蛋白抗体

hz-11228R Phospho-JunB (Thr102/Thr104)  磷酸化活化蛋白激酶B抗体

hz-11229R OTUB1  泛素特异性蛋白酶OTB1抗体

hz-11230R RAD50  DNA修复蛋白Rad50抗体

hz-5374R phospho-GIT1(Tyr510)   磷酸化G蛋白偶联受体激酶相互作用蛋白1

hz-11231R RECQL5  RecQ解旋酶样蛋白5抗体

hz-11232R RECQL5  RecQ解旋酶样蛋白5抗体

hz-11233R RPA70  单链结合蛋白70抗体

hz-11234R Miz1/ZNF60  锌指蛋白60抗体

hz-11235R GRK6  G蛋白偶联受体激酶6抗体

hz-11236R Lefty/TGF beta 4  转化生长因子β4抗体TGF β4

hz-11237R TCF12/HEB  转录因子12抗体

hz-11238R SHANK2  富含脯氨酸突触相关蛋白SHANK2抗体

hz-11239R CREB-H/CREB3L3  环腺苷酸应答元件结合蛋白H抗体

hz-11240R phospho-Tau protein(Ser202)  磷酸化微管相关蛋白抗体

hz-11241R AP2M1/AP-2?  接头相关蛋白复合体AP-2μ链1抗体

hz-11242R Phospho-AP2M1 (Thr156)  磷酸化接头相关蛋白复合体AP-2μ链1抗体

hz-11243R Rab17  RAS癌基因相关蛋白RAB17抗体

hz-11244R RAB38  G蛋白结合蛋白RAB38抗体

hz-4221R TM7SF2/DHCR14A  脱氢胆固醇还原酶14抗体

hz-4113R HMG14/HMGN1  高迁移率核小体结合蛋白1

hz-4111R G3BP1  Ras GTP酶活化蛋白结合蛋白1抗体

hz-4248R ORP150  氧气调节蛋白150抗体

hz-0630R AT1R/AGTR1  血管紧张素Ⅱ-1型受体抗体

hz-2097R AT1R/AGTR1  血管紧张素Ⅱ-1型受体抗体

hz-5376R phospho-G3BP1(Ser232)  磷酸化Ras GTP酶活化蛋白结合蛋白1抗体

hz-5384R phospho-HMGN1(Ser20+Ser24)  磷酸化高迁移率核小体结合蛋白1

hz-0517R ATF1  活化转录因子1抗体

hz-4608R CUEDC2/CUE domain containing 2  CUE结构域蛋白2抗体

hz-4223R TRAP220/MED1  甲状腺受体相关蛋白220抗体

hz-5700R phospho-TRAP220/MED1(Thr1457)   磷酸化甲状腺受体相关蛋白220抗体