少突胶质细胞跨膜蛋白抗体

英文名称    Claudin 11    

中文名称    少突胶质细胞跨膜蛋白抗体    

别    名    Oligodendrocyte Specific Protein; Oligodendrocyte transmembrane protein; Claudin 11; claudin11; claudin-11; CLDN 11; CLDN11; Oligodendrocyte transmembrane protein; OSP; OTM.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  神经生物学  信号转导  细胞凋亡      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 少突胶质细胞跨膜蛋白抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    22kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Claudin-11    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

少突胶质细胞跨膜蛋白抗体产品介绍    background:

Oligodendrocyte specific protein (OSP)is the third most abundant component of central nervous system myelin. The claudin superfamily consists of many structurally related proteins. These proteins, which include claudin 1 through 18, are located in both epithelial and endothelial cells in all tight junction bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. There is growing evidence that OSP/Claudin 11 determines the permeability between layers of myelin sheaths via focal adhesion. Its expression is highly regulated during development, suggesting that it may play an important role in the growth and differentiation of oligodendrocytes and other cells outside the CNS. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.

Subunit:
Interacts with tetraspanin-3/TSPAN3.    

少突胶质细胞跨膜蛋白抗体

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hz-1336 Lp-PL-A2 ELISA Kit  大鼠脂蛋白磷脂酶A2

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hz-1337 HSP-90 ELISA Kit  大鼠热休克蛋白90

hz-1338 HSP-70 ELISA Kit  大鼠热休克蛋白70

hz-1338 C4(Mouse Complhzent 4) ELISA Kit  小鼠补体蛋白4

hz-1338 ALT/GPT(Human Alanine Aminotransferase) ELISA Kit  人丙氨酸转氨酶/谷丙转氨酶

hz-1339 GOT/GPT(Human Aspartate aminotransferase) ELISA Kit  人天门冬氨酸转氨酶/谷草转氨酶

hz-1339 Renin(Mouse Renin) ELISA Kit  小鼠肾素

hz-1339 HSP-40 ELISA Kit  大鼠热休克蛋白40

hz-1340 HL(Human hepatic lipase) ELISA Kit  人肝脂酶

hz-1340 Alpha2-AP(Mouse Alpha2-Antiplasmin) ELISA Kit  小鼠α2抗纤溶酶

hz-1340 HSP-20 ELISA Kit  大鼠热休克蛋白20

hz-1341 Alpha2-PI(Mouse Alpha2-plasmin inhititor) ELISA Kit  小鼠α2纤溶酶抑制物

hz-1341 A Beta1-40 ELISA Kit  大鼠β淀粉样蛋白1-40

hz-1341 HPA(Human Heparanase) ELISA kit  人乙酰肝素酶

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hz-1343 IDUA(Mouse Alpha-L-iduronidase) ELISA Kit  小鼠αL艾杜糖苷酸酶

hz-1343 FRA(Human fibronection related antigen) ELISA Kit  人纤维连接素相关抗原

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