轴突生长因子CD108抗体

英文名称    CD108    

中文名称    轴突生长因子CD108抗体    

别    名    semaphorin 7A; CD 108; CD108; CD108 antigen; CDw108; H Sema K1; H Sema L; JMH; JMH blood group antigen; John Milton Hagen blood group H Sema K1; John Milton Hargen human blood group Ag; MGC126692; MGC126696; Sema domain immunoglobulin domain (Ig) and GPI membrane anchor 7A; Sema L; Sema7a; SEMAK1; SEMAL; Semaphorin 7A GPI membrane anchor; Semaphorin K1; Semaphorin L; Semaphorin7a; SEM7A_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  免疫学  生长因子和激素  转录调节因子      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Cow,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 轴突生长因子CD108抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    66kDa    

细胞定位    细胞膜 细胞外基质     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Sema7A    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

轴突生长因子CD108抗体产品介绍    background:

Semaphorin 7a is required for central and peripheral axon growth and is required for proper axon tract formation during embryonic development. Semaphorin 7a is also involved in modulating immune function. Semaphorin 7a expression is highest in the brain and increases in late embryonic and postnatal stages. The Semaphorins constitute a large family of secreted and membrane-tethered cell signaling molecules. They have functions in neural development, immunology, cardiac growth, vascular development, lung morphogenesis and axial bone patterning. Semaphorins are defined by the presence of a conserved Sema domain at the N-terminus. These proteins can be classified into eight classes depending on their structure and species origin. Classes 3 through 7 are found in vertebrates; class 3 are secreted, class 7 are GPI-anchored, and class 4 through 6 are transmembrane proteins.

Function:
Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.    

轴突生长因子CD108抗体

hz-0369P-APhz Rabbit IgM/APC  荧光素APC标记兔IgM

hz-0346P-APhz Rat IgM/APC  荧光素APC标记大鼠IgM

hz-0789P-APhz Insulin Protein /APC  荧光素APC标记猪胰岛素蛋白

hz-P0002-APhz KLH/APC  荧光素APC标记血蓝蛋白

hz-P0003-APhz OVA/APC  荧光素APC标记鸡卵白蛋白

hz-0945P-APhz HSA(Human sermu albumin)/APC  荧光素APC标记人血白蛋白

hz-2179P-APhz AACT/APC  荧光素APC标记胰糜蛋白酶

hz-0437P-hzy3 Streptavidin/Cy3  荧光素Cy3标记链霉亲和素

hz-0312P-hzy3 Avidin/Cy3  荧光素Cy3标记亲合素

hz-0362P-hzy3 Protein A/Cy3  Cy3标记蛋白A

hz-0295P-hzy3 Rabbit IgG/Cy3  荧光素Cy3标记兔IgG(细胞流式同型对照)

hz-0296P-hzy3 Mouse IgG/Cy3  荧光素Cy3标记小鼠IgG(细胞流式同型对照)

hz-0294P-hzy3 Goat IgG/Cy3  荧光素Cy3标记羊IgG(细胞流式同型对照)

hz-0293P-hzy3 Rat IgG/Cy3  荧光素Cy3标记大鼠IgG(细胞流式同型对照)

hz-0326P-hzy3 Bovine IgG/Cy3  荧光素Cy3标记牛IgG

hz-0327P-hzy3 Bovine IgM/Cy3  荧光素Cy3标记牛IgM

hz-0310P-hzy3 Chicken IgG/Cy3  荧光素Cy3标记鸡IgG

hz-0314P-hzy3 Chicken IgM/Cy3  荧光素Cy3标记鸡IgM

hz-0303P-hzy3 dog IgG/Cy3  荧光素Cy3标记狗IgG

hz-0373P-hzy3 dog IgM/Cy3  荧光素Cy3标记狗IgM

hz-0370P-hzy3 Goat IgM/Cy3  荧光素Cy3标记羊IgM

hz-0358P-hzy3 Guinea pig IgG/Cy3  荧光素Cy3标记豚鼠IgG

hz-0375P-hzy3 Guinea pig IgM/Cy3  荧光素Cy3标记豚鼠IgM

hz-0308P-hzy3 Horse IgG/Cy3  荧光素Cy3标记马IgG

hz-0374P-hzy3 Horse IgM/Cy3  荧光素Cy3标记马IgM

hz-0297P-hzy3 human IgG/Cy3  荧光素Cy3标记人IgG

hz-0345P-hzy3 human IgM/Cy3  荧光素Cy3标记人IgM

hz-0360P-hzy3 human IgA/Cy3  荧光素Cy3标记人IgA

hz-0335P-hzy3 Monkey IgG/Cy3  荧光素Cy3标记猴IgG

hz-0336P-hzy3 Monkey IgM/Cy3  荧光素Cy3标记猴IgM