IV型胶原蛋白/4型胶原蛋白/胶原蛋白4抗体

英文名称    Collagen IV    

中文名称    IV型胶原蛋白/4型胶原蛋白/胶原蛋白4抗体    

别    名    Arresten; Canstatin; COL4A1; HANAC; ICH; POREN1; Collagen Alpha 1(IV) Chain; Collagen IV Alpha 1 Polypeptide; Collagen Of Basement Membrane Alpha 1 Chain; Collagen Of Basement Membrane Alpha 2 Chain; Collagen Type IV Alpha 1; DKFZp686I14213; FLJ22259; collagen alpha-1(IV) chain preproprotein; collagen alpha-1(IV) chain preproprotein; Col4a1 protein; collagen of basement membrane, alpha-1 chain; collagen IV, alpha-1 polypeptide; collagen alpha-1(IV) chain; COL4A1 NC1 domain.    

说 明 书    0.1ml  0.2ml  1ml    

研究领域    肿瘤  细胞生物      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 IV型胶原蛋白/4型胶原蛋白/胶原蛋白4抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    165kDa    

细胞定位    细胞膜 细胞外基质 分泌型蛋白     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Collagen alpha-1(IV) chain    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

IV型胶原蛋白/4型胶原蛋白/胶原蛋白4抗体产品介绍    background:

This gene encodes the major type IV alpha collagen chain of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. [provided by RefSeq, Jul 2008]

Function:
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. 
Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.    

IV型胶原蛋白/4型胶原蛋白/胶原蛋白4抗体

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hz-3065R Phospho-CD19(Tyr531)  磷酸化CD19抗体

hz-0080R CD20  CD20抗体

hz-3792R CD21/EBV receptor  2型补体受体抗体

hz-1481R CD22/BLCAM  B淋巴细胞粘附分子CD22抗体

hz-2490R CD23/Fc EpsilonR II  CD23抗体

hz-0528R CD24  CD24抗体

hz-4263R ENaCg/γENaC  上皮钠离子通道蛋白γ抗体

hz-4264R DMRT3  睾丸特异性DMRT3蛋白抗体

hz-4267R CARF/CDKN2AIP  钙反应因子抗体

hz-0577R CD25/IL-2RA  白介素2受体a链抗体 IL-2Ra

hz-1959R CD122/IL-2RB  白介素2受体β链抗体 IL-2Rβ

hz-2570R CD26  CD26抗体

hz-2545R IL-2R gamma/CD132  白介素2受体γ链抗体

hz-0624R CD272/BTLA  B和T淋巴细胞衰减蛋白抗体

hz-4268R TBRG1  转化生长因子β调节蛋白1抗体

hz-4269R CDKN2B/p15 INK4b  细胞周期蛋白依赖性激酶抑制剂2B抗体

hz-0512R CD2AP  白细胞分化抗原CD2AP抗体

hz-3690R CD1A  T淋巴细胞CD1A抗体

hz-3786R CD1a/Cortical thymocyte antigen CD1A  T淋巴细胞CD1抗体

hz-2515R CD2  CD2抗体

hz-2205R SLAMF9/CD2F-10  CD2F-10抗体

hz-4200R SBP1/Selenium Binding Protein 1  硒结合蛋白1抗体

hz-2486R SLAMF9  CD2F-10抗体

hz-4270R CDKN2C/p18 INK4c  细胞周期蛋白依赖性激酶抑制剂2C抗体

hz-0765R CD3/CD3-ε  CD3抗体

hz-2747R Bcr  Bcr抗体

hz-3067R Phospho-Bcr(Tyr177)  磷酸化T淋巴细胞受体抗体

hz-5982R CDKN2D/p19 INK4d  细胞周期蛋白依赖性激酶抑制剂2D抗体

hz-4272R CHFR  泛素连接酶蛋白CHFR抗体

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hz-2495R CD30/TNFRSF8  CD30抗体

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hz-0195R CD31/PECAM-1  血小板内皮细胞黏附分子-1抗体

hz-2042R CD33/Siglec-3  CD33抗体