CD68抗体

英文名称    CD68    

中文名称    CD68抗体    

别    名    CD 68; CD68 antigen; CD68 molecule; DKFZp686M18236; GP110; Macrophage antigen CD68 (microsialin); macrosialin; SCARD1; Scavenger receptor class D member 1; macrosialin isoform A precursor; CD68_MOUSE; Macrosialin; Gp110; scavenger receptor class D, member 1; macrophage antigen CD68; LAMP4.    

说 明 书    0.1ml  0.2ml      

研究领域    免疫学  细胞表面分子  细胞类型标志物      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Mouse, Rat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 CD68抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    37kDa    

细胞定位    细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from mouse CD68    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

CD68抗体产品介绍    background:

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008].

Function:
Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.    

CD68抗体

hz-9813R EGFR5/CLEC14A  表皮生长因子受体5抗体

hz-9814R C2orf44  2号染色体开放阅读框44抗体

hz-9815R C2orf42  2号染色体开放阅读框42抗体

hz-9816R C2orf43  2号染色体开放阅读框43抗体

hz-9817R C2orf55  2号染色体开放阅读框55抗体

hz-9818R C2orf57  2号染色体开放阅读框57抗体

hz-9819R C2orf69  2号染色体开放阅读框69抗体

hz-1649R phospho-APP/ABPP(Tyr757)  磷酸化APP(Tyr757)淀粉样肽前体蛋白抗体

hz-9820R C2orf89  2号染色体开放阅读框89抗体

hz-9821R C2orf29  2号染色体开放阅读框29抗体

hz-9822R C3orf24  3号染色体开放阅读框24抗体

hz-9823R AAT1/C3orf15  3号染色体开放阅读框15抗体

hz-9824R C3orf17  3号染色体开放阅读框17抗体

hz-3028R phospho-APP/ABPP(Thr668)  磷酸化APP淀粉样肽前体蛋白抗体

hz-9825R C3orf18  3号染色体开放阅读框18抗体

hz-9826R C3orf21/XXYLT1  3号染色体开放阅读框21抗体

hz-5167R phospho-APP/ABPP (Thr743)  磷酸化APP淀粉样肽前体蛋白抗体

hz-5168R phospho-APP/ABPP (Ser730)  磷酸化APP淀粉样肽前体蛋白抗体

hz-9827R C3orf23  3号染色体开放阅读框23抗体

hz-9828R C3orf33  3号染色体开放阅读框33抗体

hz-5186R phospho-APP/ABPP(Thr743)  磷酸化APP淀粉样肽前体蛋白抗体

hz-9829R C3orf37  3号染色体开放阅读框37抗体

hz-9830R C3orf39  3号染色体开放阅读框39抗体

hz-1632R APPL1  衔接因子蛋白含pH域磷酸酪氨酸结合域和亮氨酸拉链蛋白1抗体

hz-9831R C3orf49  3号染色体开放阅读框49抗体

hz-9832R C3orf54  3号染色体开放阅读框54抗体

hz-9833R C3orf59/MB21D2  3号染色体开放阅读框59抗体

hz-9836R HLC8/Lung cancer related protein 8  肺癌相关蛋白8抗体

hz-9838R C17orf59  17号染色体开放阅读框59抗体

hz-9837R C17orf104  17号染色体开放阅读框104抗体

hz-9839R C17ORF39  17号染色体开放阅读框39抗体