获取电话英文名称 CCR8
中文名称 细胞表面趋化因子受体8抗体
别 名 C-C chemokine receptor 8; C-C chemokine receptor type 8;CCR-8; C-C CKR-8; CC-CKR-8; CCR8; CD_antigen=CDw198.GPR-CY6; GPRCY6; Chemokine receptor-like 1; CKR-L1; TER1; CMKBRL2; CC-chemokine receptor CHEMR1; CMKBR8; CKRL1; CCR8_MOUSE.
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 免疫学 细胞膜受体 趋化因子
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit,
产品应用 WB=1:50-100 IHC-P=1:50-100 IHC-F=1:50-100细胞表面趋化因子受体8抗体 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse CCR-8
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
细胞表面趋化因子受体8抗体产品介绍 background:
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation regulated cytokine (TARC) and macrophage inflammatory protein 1 beta (MIP1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. CCR8 expression has been reported in spleen and thymus, natural killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes. CCR8 is also believed to be alternative coreceptor with CD4 for HIV-1 infection.
Function:
Receptor for the CCL1/SCY1/TCA-3 chemokine.
细胞表面趋化因子受体8抗体
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