胆绿素还原酶抗体

英文名称    Biliverdin Reductase    

中文名称    胆绿素还原酶抗体    

别    名    Biliverdin Reductase; Biliverdin IX alpha reductase; Biliverdin reductase A; BLVR A; BLVR; BLVRA; BVR A; BVR; BVRA; zinc-metalloprotein; BIEA_HUMAN.    

说 明 书    0.2ml      

研究领域    细胞生物  免疫学  信号转导  激酶和磷酸酶  新陈代谢      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 胆绿素还原酶抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    33kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human BLVRA/Biliverdin Reductase    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.    

胆绿素还原酶抗体产品介绍    background:

In human liver cytosolic fractions, four forms of biliverdin reductase have been identified, including two biliverdin-IX Beta reductases and two biliverdin-IX Alpha reductases, designated isozymes I and II and isozymes III and IV, respectively. Biliverdin reductase A (BLVRA), also designated biliverdin-IX Alpha-reductase, belongs to the GFO/iIDH/MocA family and the biliverdin reductase subfamily. The gene that encodes this cytoplasmic protein maps to chromosome 7p14-cen. BLVRA reduces biliverdin IX ?(the ?methene bridge of the open tetrapyrrole) to bilirubin with the concomitant oxidation of an NADH or NADPH cofactor (bilirubin + NADP+ = biliverdin + NADPH). BLVRA is expressed primarily in liver.

Function:
Biliverdin Reductase (BVR) catalyzes the final step in the heme metabolic pathway, the reduction of biliverdin IX{alpha} to bilirubin, with the concomitant oxidation of a NADH or NADPH cofactor. The enzyme remains unique among all biological catalysts described to date in having a dual pH/cofactor-dependent activity profile. Human biliverdin reductase (hBVR) has been recently shown to be a Ser/Thr/Tyr kinase in the MAPK insulin/insulin-like growth factor 1 (IGF1)-signaling cascade. BVR together with its substrate, biliverdin, and product, bilirubin, have recently been revealed to be important players in cellular signal transduction pathways, gene expression and oxidative response. These features make BVR unusually interesting and unique among all enzymes characterized to date.     

胆绿素还原酶抗体

hz-3019R phospho-eIF4EBP1(Thr37/46)  磷酸化4E结合蛋白1抗体

hz-3720R phospho-eIF4EBP1/4EBP1(Ser65/Thr70)  磷酸化eIF4E结合蛋白抗体

hz-5334R phospho-EIF4EBP1(Ser100)  磷酸化eIF4E结合蛋白抗体

hz-5337R phospho-EIF4EBP1(Ser111)  磷酸化eIF4E结合蛋白抗体

hz-2913R EIF5  真核翻译起始因子5抗体

hz-3839R 4EBP2  eIF4E结合蛋白2抗体

hz-1440R Cytokeratin 5/CK5  细胞角蛋白5抗体

hz-1126R 5-HT  5-羟色胺抗体

hz-1597R HRPT2/CDC73/Parafibromin  甲状旁腺功能亢进蛋白2抗体（细胞分裂周期73）

hz-1124R 5-HTR1A  5-羟色胺受体1A抗体

hz-1663R THOC2  转录因子THOC2抗体

hz-1665R VEGF  血管内皮生长因子抗体

hz-1677R DNA Ligase IV/LIG4  DNA连接酶4抗体

hz-1125R 5-HTR1B 5-羟色胺受体1B抗体

hz-1892R 5-HTR2B 5-羟色胺受体2B抗体

hz-1056R 5-HTR2A 5-羟色胺受体2A抗体

hz-1893R 5-HTT  5-羟色胺转运蛋白抗体

hz-2126R 5-HTR3  5-羟色胺受体3抗体

hz-2127R 5-HTR4  5-羟色胺受体4抗体

hz-0526R 5 lipoxygenase/ALOX5  5-脂氧合酶抗体

hz-3251R Phospho-5-Lipoxygenase(Ser271)  磷酸化5-脂氧合酶抗体

hz-3252R Phospho-5-Lipoxygenase(Ser663)  磷酸化5-脂氧合酶抗体

hz-3874R ALOX12/12 Lipoxygenase  12脂氧合酶抗体

hz-2036R Penicillin G  青霉素G抗体

hz-1278R 8-OHdG  8-羟基脱氧鸟苷抗体

hz-2053R RYBP/APAP1/CD337  凋亡相关蛋白1抗体

hz-2054R Nkx2.5/Cardiac-specific homeobox 1  心脏特异性同源盒转录因子NKX2.5抗体

hz-4235R ADORA1  腺苷A1A受体抗体

hz-2077R AMP deaminase 1  腺苷单磷酸脱氨酶1抗体

hz-1456R A2AR/Adenosine A2a receptor  腺苷A2A受体抗体

hz-0094R AACT-Alpha1/A1ACT  α-1抗胰糜蛋白酶抗体