获取电话英文名称 ACCN1
中文名称 脑钠通道蛋白1抗体
别 名 ACCN; ASIC2a; BNaC1; ASIC2; ASICs2 ACCN1_HUMAN; Acid sensing ion channel 2; Acid-sensing ion channel 2; Amiloride sensitive brain sodium channel; Amiloride sensitive cation channel 1 neuronal (degenerin); Amiloride sensitive cation channel 1 neuronal; Amiloride-sensitive brain sodium channel; Amiloride-sensitive cation channel 1, neuronal; Amiloride-sensitive cation channel neuronal 1; ASIC2; ASIC2a; BNaC1; BNC1; Brain sodium channel 1; Degenerin; hBNaC1; Mammalian degenerin homolog; MDEG; Neuronal amiloride sensitive cation channel 1.
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 免疫学 神经生物学 通道蛋白 淋巴细胞 t-淋巴细胞
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 脑钠通道蛋白1抗体（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
细胞定位 细胞浆 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ACCN1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
脑钠通道蛋白1抗体产品介绍 background:
Degenerin/epithelial sodium channel (DEG/ENaC) superfamily members are amiloride-sensitive sodium channels that contain intracellular N- and C-termini, 2 two hydrophobic transmembrane regions and a cysteine-containing extracellular loop. Acid sensing ion channel ASIC1, also designated ACCN2, BNAC2 and ASIC1a, is present in brain as a 4.3-kb transcript with localization to rat dorsal root ganglia. In situ hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety. ASIC2, also designated amiloride-sensitive cation channel 1, neuronal (ACCN1), mammalian degenerin, BNAC1 (MDEG) and brain Na+ channel 1, mediates the normal detection of light touch. ASIC2 mRNA is abundant in brain, specifically in neurons. ASIC2 is expressed as 2.7- and 3.7-kb transcripts in brain and spinal cord tissues. ASIC3, also designated ASIC3, SLNAC1 and TNaC1, mediates detection of lasting pH changes and is involved in modulating moderate- to high-intensity pain sensation. ASIC4, also designated ACCN4 and BNAC4, is abundant in pituitary gland and is also present in the inner ear.
Function:
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.
脑钠通道蛋白1抗体公司更多热销抗体产品如下：
hz-9045R TRPM8 “冷”蛋白TRPM8抗体
hz-9046R TRPM3 瞬时受体电位离子通道蛋白3抗体（M亚家族）
hz-9047R TRPM5 瞬时受体电位离子通道蛋白5抗体（M亚家族）
hz-9048R TRPM6 瞬时受体电位离子通道蛋白6抗体（M亚家族）
hz-9049R TRPM1 瞬时受体电位离子通道蛋白1抗体（M亚家族）
hz-9051R TRPM4 瞬时受体电位离子通道蛋白4抗体（M亚家族）
hz-9052R DIS3L 有丝分裂控制样蛋白DIS3L抗体
hz-9053R DIS3L2 有丝分裂控制蛋白样DIS3L2抗体
hz-9054R DOM3Z DOM3Z蛋白抗体
hz-9055R DR1 protein 转录下调蛋白1抗体
hz-9056R Dermokine beta Dermokine β蛋白抗体
hz-9057R DPCR1 DPCR1蛋白抗体
hz-9058R DHFR 二氢叶酸还原酶抗体
hz-9059R DVL2 蓬乱蛋白2抗体
hz-9060R phospho-DVL2(Thr224) 磷酸化蓬乱蛋白2抗体
hz-9061R ODZ3/Teneurin 3 固生蛋白3抗体
hz-9062R ACCSL ACCSL蛋白抗体
hz-9063R FAM135B FAM135B蛋白抗体
hz-9064R FAM166A FAM166A蛋白抗体
hz-9065R HIDE1/C19orfC38 19号染色体开放阅读框38抗体
hz-9066R HIG1/HIGD1A 缺氧诱导基因1蛋白抗体
hz-9067R HIP1R/HIP12/HIP3 亨丁顿舞蹈症相互作用蛋白12抗体
hz-9068R HMBS/PBGD 卟胆原脱氨酶抗体
hz-9069R HN1/ARM2 雄激素调节蛋白2抗体
hz-9070R HN1L 雄激素调节样蛋白抗体
hz-9071R HORMAD2 异质核糖核蛋白U2样蛋白抗体
hz-9072R HRP2 肝癌衍生生长因子2抗体
