三磷酸腺苷酶家族蛋白3A抗体

英文名称    ATAD3A    

中文名称    三磷酸腺苷酶家族蛋白3A抗体    

别    名    AAA-ATPase TOB3; ATAD3B; ATAD3C; Atad3a; ATPase family AAA domain containing protein 3A; ATPase family AAA domain-containing protein 3; ATPase family, AAA domain containing 3A; FLJ10709; FLJ35514; AAA ATPase TOB3; AAA-TOB3; ATPase family AAA domain containing protein 3B; ATPase family, AAA domain containing 3B; ATPase family, AAA domain containing, member 3B; TOB3; ATD3A_HUMAN; ATAD3A/B/C.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  免疫学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 三磷酸腺苷酶家族蛋白3A抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    71kDa    

细胞定位    细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human ATAD3A    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

三磷酸腺苷酶家族蛋白3A抗体产品介绍    background:

The AAA ATPase family of molecular chaperones are characterized by a highly conserved AAA motif. Composed of 200-250 residues, the AAA domain contains Walker homology sequences and imparts ATPase activity. Members of the AAA ATPase family act as DNA helicases as well as transcription factors and are thought to be involved in several cellular functions such as cell-cycle regulation, protein proteolysis, organelle biogenesis and vesicle-mediated protein transport. Mitochondrial membrane proteins ATAD3A and ATAD3B contribute to the stabilization of nucleoids which are large mitochondrial DNA (mtDNA)-protein complexes. ATAD3A/B may participate in the transformation pathway and the chemosensitivity of oligodendrogliomas. The genes encoding ATAD3A/B/C maps to human chromosome 1, which houses over 3,000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome.

Function:
Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis.    

三磷酸腺苷酶家族蛋白3A抗体公司更多热销抗体产品如下：

hz-6850R TPST1  酪蛋白硫酸转移酶1抗体

hz-6851R TPST2  酪蛋白硫酸转移酶2抗体

hz-6852R AGPA/Alpha 1 Acid Glycoprotein  α1酸性糖蛋白1/类粘蛋白1抗体

hz-6853R PIWIL4  piwi样4蛋白抗体

hz-6854R CARD7/NALP1  凋亡加强结构域蛋白7抗体

hz-6855R NALP4  癌/睾丸抗原58抗体

hz-6856R NLRP10  富含亮氨酸重复结构域蛋白10抗体

hz-6857R beta COP  β衣被蛋白抗体

hz-6858R Caspase 4/Caspase 11  半胱胺酸蛋白酶4/11抗体

hz-6859R Caspase 14  半胱胺酸蛋白酶蛋白14抗体

hz-6860R Caspase 5  半胱胺酸蛋白酶蛋白5抗体

hz-6861R Fhz1A  前列腺素E受体4相关蛋白抗体

hz-6862R LANPL  富含亮氨酸样酸性核蛋白抗体

hz-6863R MALT1  粘膜相关淋巴组织淋巴瘤转运蛋白1抗体

hz-6864R NALP12  NALP12抗体

hz-6865R NALP6  富含亮氨酸重复结构域蛋白6抗体

hz-6866R NLRP7  富含亮氨酸重复结构域蛋白7抗体

hz-6867R NLRP9  富含亮氨酸重复结构域蛋白9抗体

hz-6868R ARMER  ARMER抗体

hz-6869R HBXIP  乙型肝炎病毒X蛋白相互作用蛋白

hz-6870R ILP2  抑制细胞凋亡样蛋白2抗体

hz-6871R Interferon alpha 6  干扰素α6抗体

hz-6872R Rffl/RING finger protein 189  环指蛋白189抗体

hz-6873R CERKL  视网膜色素变性蛋白26抗体

hz-6874R Catalase  过氧化氢酶抗体

hz-6875R Adenylate kinase 2/AK2  腺苷酸激酶1抗体

hz-6876R FMRP/FMR1  脆性X智力低下蛋白抗体

hz-6877R IFRD1  干扰素相关发育调节蛋白1抗体（神经生长因子诱导蛋白PC4）