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仪器信息网试剂标物化学试剂有机试剂激动素

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激动素

激动素

价格：￥ 1

品牌：AMRESCO

供货周期：现货

货号：hz108959

规格：g/mg

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详细信息

详细信息

激动素

植物细胞培养级, ≥99.0% (HPLC)

Product Name: Kinetin

别名:	激动素 ;6-糠氨基嘌呤
CAS号:	525-79-1
分子式:	C₁₀H₉N₅O
分子量:	215.21
EINECS编号:	208-382-2
MDL号:	MFCD00075757

激动素

介绍:	溶于水，易溶于稀盐酸或氢氧化钠碱液；微溶于甲醇和乙醇。
特定比重:	1.489
生化和生理学机理:	Description: IC50 Value: N/A Kinetin (N6-furfuryladenine) belongs to a group of plant growth hormones involved in cell division, differentiation and other physiological processes. Kinetin is one of the widely used components in numerous skin care cosmetics and cosmeceuticals, such as Valeant products kinerase. Recently, kinetin has the potential to be a treatment for the human splicing disease familial dysautonomia. in vitro: Kinetin-induced cell death reflected by the morphological changes of nuclei including their invagination, volume increase, chromatin condensation and degradation as well as formation of micronuclei showed by AO/EB and 4,6-diamidino-2-phenylindol staining was accompanied by changes including increase in conductivity of cell electrolytes secreted to culture media, decrease in the number of the G1- and G2-phase cells and appearance of fraction of hypoploid cells as the effect of DNA degradation without ladder formation [1]. The plant cytokinin kinetin dramatically increases exon 20 inclusion in RNA isolated from cultured FD cells [3]. in vivo: Subjects received 23.5 mg/Kg/d for 28 d. An increase in WT IKBKAP mRNA expression in leukocytes was noted after 8 d in six of eight individuals; after 28 d, the mean increase compared with baseline was significant (p = 0.002) [2]. Toxicity: On mice with leukaemia P388, kinetin has no effect on the tumour growth, and it appears to be toxic at the dose of 25 mg/kg [4]. Clinical trial: N/A

激动素

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