Product Name: Oxaliplatin
别名: | (反-1,2-环己烷二胺)草酸铂(II);奥沙利铂 |
CAS号: | 61825-94-3 |
分子式: | C8H14N2O4Pt |
分子量: | 397.29 |
MDL号: | MFCD00866327 |
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介绍: | Oxaliplatin is an anti-tumor agent with activity against colorectal cancer; cytotoxicity follows the formation of adducts with DNA. |
贮存: | 储存温度 2-8°C |
敏感性: | 热敏感 |
生化和生理学机理: | Oxaliplatin is a platinum-based antineoplastic agent that is used in cancer chemotherapy. Oxaliplatin is an anti-tumor agent with activity against colorectal cancer; cytotoxicity follows the formation of adducts with DNA. Oxaliplatin forms platinum-DNA adducts. Oxaliplatin causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. |