获取电话白藜芦醇
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Product Name: Resveratrol
| 别名: | 白藜芦醇 ;芪三酚，3,4',5-三羟基芪，(E)-5-[2-(4-羟苯基)-乙烯基]-1,3-苯二酚 |
| CAS号: | 501-36-0 |
| 分子式: | C14H12O3 |
| 分子量: | 228.24 |
| MDL号: | MFCD00133799 |
白藜芦醇
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| 介绍: | 无味、完全溶解于乙醇。 |
| 用途: | COX?1选择性抑制剂。 白藜芦醇是一种酚类植物抗毒素,发现于葡萄皮和其他植物中。它具有细胞内抗氧化活性激活去乙酰化酶SIRT1。白藜芦醇的抗糖尿病、神经保护和抗脂特性都可能是去乙酰化酶SIRT1激活所致。 |
| 特定比重: | 1.359 |
| 贮存: | 储存温度-20°C |
| 生化和生理学机理: | Resveratrol is a phenolic phytoalexin found in grape skin and other plants. Resveratrol produced neurotrophic effects on cultured DA neurons. Resveratrol could attenuate oxidant-induced mitochondrial damage in embryonic rat cardiomyocytes by inactivating GSK-3β via cGMP/PKG signaling pathway independent of NO-related mechanism. Because Resveratrol has anti-inflammatory, anti-oxidant, and hypotriglyceridemic effects, its supplementation may beneficially affect the increased cardiovascular risk of healthy smokers. Resveratrol merits investigation as a potential cancer chemopreventive agent in humans. trans-Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. trans-Resveratrol is also a selective inhibitor of cyclooxygenase-1 (COX-1). It inhibits COX and peroxidase activities of COX-1 with ED50 values of 15 and 3.7 ?M, respectively; with essentially no inhibition of the COX activity of COX-2. |