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Apolipoprotein M(APOM)antibody
Cat.#: 2675-1
Rabbit Monoclonal Antibody
Clone ID: EPR2904
Swiss Prot: O95445
Mol Weight: 26kDa
Size: 100ul
Description
Apolipoprotein M (ApoM) is a novel apolipoprotein mainly present in high-density lipoprotein (HDL) (1,2). It belongs to the lipocalin protein superfamily and may bind a small but so far unknown lipophilic ligand. It is secreted without cleavage of its hydrophobic signal peptide, which probably anchors ApoM in the phospholipid moiety of plasma lipoproteins. Recent studies suggest that ApoM may affect HDL metabolism and have anti-atherogenic functions (2), including possible mechanisms of increased formation of pre-ss HDL, enhanced cholesterol mobilization from foam cells, and increased antioxidant properties (1). In addition to hepatocytes, ApoM is highly expressed in kidney proximal tubule cells (2).
Recommended Applications
WB, IHC, FC
Applications and Recommended Dilution Factors
WB: 1:2,000 - 10,000
IHC: 1:100 - 250
FC: 1:50
Species Reactivity
Human
Products Data
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Western blot analysis on (A) human plasma and (B) HDL cell lysates using anti-Apolipoprotein M RabMAb (cat. #2675-1).
Immunohistochemical analysis of paraffin-embedded human liver tissue using anti- ApoM RabMAb (cat. #2675-1).
Specificity
A synthetic peptide corresponding to residues in human Apolipoprotein M was used as an immunogen.
Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Alternative Names
APOM antibody, G3a antibody, HSPC336 antibody, MGC22400 antibody, NG20 antibody, Apolipoprotein M antibody, Protein G3a antibody
Description References
1. Dahlbäck B, et al. Cell Mol Life Sci. 66(4):559-64, 2009 2. Christoffersen C, et al. Scand J Clin Lab Invest. 66(7):631-7, 2006