布鲁克出席ASMS2022:将带来质谱最新技术及相关研讨会

第70届美国质谱年会（70th ASMS Conference on Mass Spectrometry and Allied Topics）将于明尼苏达州（Minnesota）当地时间2022年6月5-9日（北京时间 2022年6月6-10日）在美国明尼阿波里斯市会议中心召开（Minneapolis Convention Center）。布鲁克在本次ASMS期间将开展单细胞质谱、质谱成像、质谱在制药领域应用、4D蛋白质组学技术等主题的研讨会日程。

Plenary Session: Enhancing Workflow Capabilities for Translational Mass Spectrometry

08:30-08:45 Welcome & Introduction

Rohan A. Thakur, Ph.D., President, Life Sciences Mass Spectrometry Division, Bruker, Fällanden, Switzerland

08:45-09:05 Proteomics at Scale – Actionable Insights to Drug Discovery & Translational Research

Ashok Dongre, Ph.D., Director & Head Proteomics, Bristol-Myers Squibb, USA

09:05-09:25 Single cell based diagnostics: translation imaging mass spectrometry

Prof. Ron Heeren, Ph.D., Director and Division Head Imaging Mass Spectrometry, Maastricht MultiModal Molecular Imaging Institute, M4i, Maastricht University, Maastricht, Netherlands

09:25-09:45 Benefits of Collisional Cross Section Assisted Precursor Selection for Cross-linking Mass Spectrometry and Glycoproteomics

Prof. Albert J. R. Heck, Ph.D., Distinguished Faculty Professor, Utrecht University, Scientific Director, Netherlands Proteomics Centre, Utrecht, Netherlands

09:45-10:15 Break

10:15 Start of Breakout Sessions

Breakout #1 Proteomics – Enhancing Workflow Capabilities of Single Cell and Translational Proteomics

10:15-10:30 Analysis of a single cell to the plasma proteome

Chris Adams, Ph.D., Business Development Director, Global Bioinformatics, Life Science Mass Spectrometry, Bruker Daltonics, Billerica, MA, USA

10:30-10:55 Nanoparticle-based enrichment coupled with Bruker timsTOF Pro 2 platform facilitates unbiased and reproducible plasma proteomics for biomarker discovery at scale

Bruce Wilcox, Ph.D., VP Proteomics, PrognomiQ, San Mateo, CA, USA

10:55-11:20 High sensitivity and deep coverage immunopeptidomics on the timsTOF Pro 2 and SCP

Prof. Stefan Tenzer, Ph.D., Head of Mass Spectrometry Core Facility, University Medical Center, Mainz, Germany

11:20-11:45 Unraveling multi-level tissue heterogeneity at single-cell and low input using the timsTOF SCP

Claudia Ctortecka, Ph.D., Postdoctoral Fellow, Carr Laboratory, Broad Institute of MIT and Harvard, Cambridge, MA, USA

11:45-12:00 Break

12:00-12:25 Boosting proteome depth of coverage by ion mobility fractionation in combination with PASEF approaches on a TIMS-QTOF instrument

Stanley Stevens, Ph.D., Associate Professor, Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, FL, USA

12:25-12:50 A Fit-for-Purpose Approach to Detect Amino Acid Substitutions in Shotgun Proteomics

Matthew Champion, Ph.D., Associate Professor, Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN, USA

 Breakout #2 Pharma/BioPharma - Enhancing Workflow Capabilities in Pharma and Biopharma

10:15-10:30 Introduction

Mike Greig, Ph.D., Director, Pharma/BioPharma Americas, Bruker Daltonics, Billerica, MA, USA

10:30-11:05 Large-Scale Mass Spectrometry Profiling for Accelerated Biomarker Discovery

Jeramie Watrous, Ph.D., Co-Founder and Head of Analytical R&D, Sapient, San Diego, CA, USA

11:05-11:40 Mapping progressively larger RNAs without front-end separations

Dan Fabris, Ph.D., Harold S. Schwenk Sr. Distinguished Chair in Chemistry, Department of Chemistry, University of Connecticut, Mansfield, CT, USA

11:40-12:00 Break

12:00-12:30 High-Throughput Host Cell Protein Analysis in Industrial Biotechnology

Christian Jörgensen, Ph.D., Novozymes A/S, Bagsvaerd, Denmark

12:30-1:00 Rapid Characterization of Bispecific Antibodies using Phase Appropriate LC-MS Strategy

Na Parra, Ph.D., Co-Founder & Executive Vice President of Marketing, LiVeritas Biosciences, South San Francisco, CA, USA

Breakout #3 Imaging - Enhancing Workflow Capabilities through Spatial Contextualization

10:15-10:25 Introduction

Mike Easterling, Ph.D., Business Unit Manager, Imaging/MRMS, Bruker Daltonics, Billerica, MA, USA

10:25-10:45 Behind the scenes with the PC-mass tag developers

Mark Lim, Ph.D., Executive Vice President and Chief Scientific Officer, AmberGen Inc., Watertown, MA, USA

10:45-11:15 First Impressions of the MALDI HiPLEX-IHC Workflow

Reid Groseclose, Ph.D., Director/GSK Fellow, GlaxoSmithKline, Philadelphia, PA, USA

11:15-11:45 Maximizing Data Generation for Rare Diseases in Biopharma

Joey Latham, Ph.D., Senior Director, Bioanalytical Science at PTC Therapeutics, Mountain View, CA, USA

11:45-12:00 Break

12:00-12:30 Preclinical Applications of Targeted Drug and Protein Imaging

John Bowling, Ph.D., Staff Scientist, Analytical Technologies Center, St. Jude Children's Research Hospital, Memphis, TN, USA

12:30-1:00 Multiplexing Spatial Proteomics of Matrix Biology in Human Health and Disease

Peggi Angel, Ph.D., Associate Professor, Department of Cell & Molecular Pharmacology & Experimental Therapeutics, Medical University of South Carolina, Charleston, SC, USA