Waters公司最新推出UPSFC系统，受到广泛关注

　　美国亚特兰大，佐治亚州，2011年3月14日，沃特斯公司在Pittcon展会期间举行了新闻发布会，约100多名色谱、质谱学界的专家参加了此次发布会。

Waters新闻发布会现场

Waters公司全球市场副总裁Rohit Khanna博士

　　在新闻发布会上，沃特斯公司今天宣布推出了将亚2微米颗粒技术优势和高效的超临界流体色谱(SFC)相结合的、整体全新设计的“Waters ACQUITY UPSFC ®™系统”。该系统基于沃特斯UPLC技术，运行时间减少到1/10,减少溶剂达95%，使分析成本减少99%，同时更加绿色；可以替代目前分析实验室用于手性和非手性分离的正相色谱。

　　Waters ACQUITY UPSFC ®™系统使科学家使用二氧化碳作为流动相进行正向色谱分离，取代有毒的有机试剂，在仪器的一生中能够节省大量费用。Waters ACQUITY UPSFC系统在实验室研究、工业常规实验室中较HPLC具有明显的优势。

Waters ACQUITY UPSFC ®™系统

　　原文

　　Waters Corporation (WAT:NYSE) announced today the introduction of the Waters® ACQUITY UPSFC™ System, a holistically designed analytical system combining the advantages of sub-2-µm particle technology and the efficiency of supercritical fluid chromatography (SFC). Built on proven Waters UltraPerformance LC® (UPLC®) technology, this new system offers up to 10X shorter run times, reduces solvent usage by as much as 95%, and cuts the cost of analyses by as much as 99% while giving laboratories a greener alternative to normal phase chromatography for chiral and achiral separations.

　　Waters ACQUITY® UPSFC System enables scientists to conduct normal phase chromatographic separations using carbon dioxide as the primary mobile phase rather than expensive and toxic solvents saving laboratories tens of thousands of dollars over the lifetime of an instrument. The newest member of Waters family of ACQUITY systems, the Waters ACQUITY UPSFC System offers laboratories significant advantages over traditional HPLC for routine UPSFC separations in research or regulated laboratories across many industries.

　　“In 2004, Waters revolutionized liquid chromatography with the introduction of sub-two micron UPLC separations resulting in significantly better data quality. Today, this proven and reliable technology offers that same potential for analytical supercritical fluid chromatography,” said Harbaksh Sidhu, General Manager, Waters SFC Operations. “As the newest member of Waters family of ACQUITY systems, the ACQUITY UPSFC System provides the same impressive separation, resolution, and speed attributes of UPLC with the outstanding green benefits of SFC.”

　　Using specially designed Viridis™ Columns the ACQUITY UPSFC System offers the ruggedness and dependability scientists are looking for, with the ease of use they’ve come to expect from liquid chromatography. The system is fully compatible with Waters industry-leading Empower™ and MassLynx™ informatics software and Waters line of UV and mass detectors.

　　Performance at Its Peak

　　Supercritical fluids share the physical properties of both a gas and a liquid and exhibit the positive chromatographic qualities of both. Relative to HPLC solvents, their low viscosity and high solute diffusivity result in faster analysis times, lower backpressure, shorter re-equilibration times and higher throughput without loss in efficiency.

　　For chiral and achiral separations this means greater signal-to-noise ratios, better peak shapes, and higher peak capacity enabling scientists to rapidly confirm the purity of compounds down to the 0.01% level, determine the enantiomeric excess, or when coupled to mass spectrometry, confirm compound identity.

　　Getting Laboratories to Where They Want to Go

　　In the 1990s, as the number of chiral drugs exceeded the number of achiral drugs, the FDA published regulatory guidance regarding enantiomeric drug compounds. SFC quickly caught on with scientists involved in drug discovery and found its niche in purification of chiral compounds. With advancements in instrument and column technology, and a focus on sustainability, the advantages of SFC have not gone unnoticed by other scientists and SFC is experiencing a resurgence in applications areas not limited to just purification but also analysis including:

Fossil fuels and hydrocarbons

• Agrichemicals
• Polymers
• Explosives and propellants
• Lipids
• Carbohydrates
• Foods and flavors
• Natural products
• Industrial chemicals
• Metal chelates and organometallic compounds