TOPAS雾化气溶胶发生器ATM220

一、仪器简介

喷雾气溶胶发生器大多具有特殊设计的喷嘴，压缩空气通过一个环形隙缝吹入将要被雾化的液体中，空气喷射口和液体之间的剪切力在这个所谓的环形缝隙中充分分散液滴，形成细小的气溶胶颗粒，而惯性碰撞器是捕获尺寸大的气溶胶颗粒而返回液体容器，使得输出颗粒粒径主要分布在2μm以下。

二、仪器应用

l 空气过滤器材的测试：

通过使用气溶胶发生器产生高浓度的颗粒，且颗粒半径接近MPPS，用于检测颗粒的过滤效率及检测过滤器渗漏的位置，常用的气溶胶材料包括DEHS、DOP、Emery 3004、盐溶液及PSL球等。

l 气溶胶测量装置的调校和检测：

雾化单分散PSL小球以进行仪器校准，如气溶胶粒径谱仪、激光粒子计数器、气溶胶光度计等，同样也是雾化发生器典型应用。

l 气溶胶基础研究

l 吸入毒性研究

l 流场示踪

l 大型风洞研究

l 生物安全柜检测（DIN EN 12469要求0.12微米的颗粒）

三、仪器规格参数

• Deng, Y. and Inomata, S. and Sato, K. and Ramasamy, S. and Morino, Y. and Enami, S. and Tanimoto, H. Temperature and acidity dependence of secondary organic aerosol formation from alpha-pinene ozonolysis with a compact chamber system Atmos. Chem. Phys. 21 (2021) 8, 5983 - 6003
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• Kretzschmar, B.S.M.; Bergelt, P.; Göhler, D.; Firmbach, F.; Köcher, R.; Heft, A.; Stintz, M. & Grünler, B. Modulation of silica layer properties by varying the granulometric state of tetraethyl orthosilicate precursor aerosols during combustion chemical vapour deposition (CCVD) Aerosol Sci. Technol. 54 (2020) 10, 1124 - 1134
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• Frijns E., Verstraelen S., Stoehr L. C., Laer J. V., Jacobs A., Peters J., Tirez K., Boyles M. S. P., Geppert M., Madl P., Nelissen I., Duschl A. and Himly M. A Novel Exposure System Termed NAVETTA for In Vitro Laminar Flow Electrodeposition of Nanoaerosol and Evaluation of Immune Effects in Human Lung Reporter Cells Environ. Sci. Technol. 51 (2017) 9, 5259 - 5269
  dx.doi.org/10.1021/acs.est.7b00493

• Fiala P., Göhler D., Wessely B., Stintz M., Lazzerini G. M. and Yacoot A. Evaluation of preparation methods for suspended nano objects on substrates for dimensional measurements by atomic force microscopy Beilstein J. Nanotechnol. 8 (2017) 0, 1774 - 1785
  dx.doi.org/10.3762/bjnano.8.179

• Göhler, D.; Große, S.; Bellendorf, A.; Falkenstein, T.A.; Ouaissi, M.; Zieren, J.; Stintz, M. & Giger-Pabst, U. Hyperthermic intracavitary nano-aerosol therapy (HINAT) as improved approach for pressurised intraperitoneal aerosol chemotherapy (PIPAC): Technical description, experimental validation and first proof of concept. Beilstein J. Nanotechnol. 8 (2017) 0, 2729 - 2740
  dx.doi.org/10.3762/bjnano.8.272

• Tarik M., Foppiano D., Hess A. and Ludwig C. A Practical Guide on Coupling a Scanning Mobility Sizer and Inductively Coupled Plasma Mass Spectrometer (SMPS-ICPMS) J. Vis. Exp. 125 (2017) 0, e55487
  dx.doi.org/10.3791/55487

• Zeng L. and Weber A. P. Aerosol synthesis of nanoporous silica particles with controlled pore size distribution J. Aerosol Sci. 76 (2014) 0, 1 - 12
  dx.doi.org/10.1016/j.jaerosci.2014.05.003