Vanillylacetone

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产品名称：Vanillylacetone

产品别名：见爱必信官网

英文别名：Vanillylacetone

靶点：Phenols

CAS：122-48-5

纯度：98%

外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）

描述：Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic and anti-tumor properties. Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways. Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells.

溶解性：

体外研究：

Zingerone is a nontoxic methoxyphenol with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic properties. Zingerone (0-2 mM) decreases neruoblastoma cell survival. Zingerone (0-2 mM) reduces cyclin D1 expression, increases cleavage of caspase-3 and PARP-1 in BE(2)-M17 cells.

体内研究：Zingerone (50, 100 ?mg/kg, p.o. daily for 21?days) protects against alloxan-induced diabetes via alleviation of oxidative stress and inflammation in rat. Zingerone (10 mg/kg, i.p.) inhibits tumor progression through mitotic arrest, failure of cell division, and stimulation of apoptosis.

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