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磷酸化血管内皮生长因子受体2抗体
英文名称 phospho-VEGFR2 (Tyr951)
中文名称 磷酸化血管内皮生长因子受体2抗体
别 名 VEGFR2(Phospho-Tyr951); VEGFR2(Phospho-Y951); p-VEGFR2(Tyr951); p-VEGFR2(Y951); CD309; CD309 antigen; Fetal liver kinase 1; FLK-1; FLK1; KDR; Kinase insert domain receptor (a type III receptor tyrosine kinase); Kinase insert domain receptor; KRD1; Ly73; Protein tyrosine kinase receptor FLK1; Protein-tyrosine kinase receptor flk-1; Tyrosine kinase growth factor receptor; Vascular endothelial growth factor receptor 2; VEGFR 2; VEGFR; VEGFR-2; VEGFR2; VGFR2_HUMAN.
产品类型 磷酸化抗体
研究领域 心血管 细胞生物 免疫学 神经生物学 生长因子和激素
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Rabbit,
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 147kDa
细胞定位 细胞核 细胞浆 细胞膜 分泌型蛋白
性 状 Lyophilized or Liquid
浓 度 1mg/ml
免 疫 原 KLH cunjugated Synthetic phosphopeptide derived from human VEGFR2 around the phosphorylation site of Tyr951:KD(p-Y)VG
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 Hemangioblast Marker
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009].
细胞膜受体(Membrane Receptors)
成血管细胞标志物
VEGFR-2是一种细胞膜受体激酶,对血管内皮生长因子-VEGF有高度的亲和性,主要功能是参与血管内皮细胞生长和血管生成的调控,参与血管内皮细胞的生长。用于各种恶性肿瘤的研究。