![1.png 1.png](https://img1.17img.cn/17img/images/201906/uepic/d13c6712-03e2-43bf-8f7d-f7d9438be7a4.jpg)
胆固醇21-羟化酶抗体
英文名称 CYP21A2
中文名称 胆固醇21-羟化酶抗体
别 名 Cytochrome P450 21; cytochrome P450, family 21, subfamily A, polypeptide 2; 21-OH; 21OHA; 21OHB; CA21H; CAH1; CHOLESTEROL 21-HYDROXYLASE; CPS1; CYP21; Cyp21-ps1; Cyp21a1; CYP21A2; Cyp21a2-ps; CYP21B; CYP21OH-A; MGC150536; MGC150537; MGC156449; Oh21-1; Oh21-2; P450C21; P450c21B; CYP21A2; CP21A_HUMAN.
研究领域 肿瘤 细胞生物
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse,
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
细胞定位 细胞浆 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CYP21:101-200/494
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].