腺泡状软组织肉瘤结构域蛋白ASPC抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 腺泡状软组织肉瘤结构域蛋白ASPC抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Glut4 is a twelve pass transmembrane protein (12TM) whose carboxy-terminus may dictate its cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity. 腺泡状软组织肉瘤结构域蛋白ASPC抗体TUG (ASPL in humans) regulates the trafficking of glucose via Glut4. Full-length TUG forms a complex with Glut4 and in 3T3-L1 adipocytes and this complex is present in unstimulated cells and is disassembled by insulin. TUG acts by trapping endocytosed Glut4 and tethering it intracellularly. Insulin mobilizes this pool of retained Glut4 by releasing the tether.

腺泡状软组织肉瘤结构域蛋白ASPC抗体Also known as:

Alveolar soft part sarcoma chromosomal region candidate gene 1 protein; Alveolar soft part sarcoma chromosome region candidate 1 (human); Alveolar soft part sarcoma locus; ASPC; ASPC1_HUMAN; ASPCR 1; ASPCR1; ASPL; ASPS; ASPSCR 1; Aspscr1; FLJ45380; RCC 17; RCC17; renal cell carcinoma gene on chromosome 17; renal cell carcinoma papillary 17; Renal papillary cell carcinoma protein 17; Tether containing a UBX domain for GLUT4; Tether containing UBX domain for GLUT4; TUG; UBX domain containing protein 9; UBX 腺泡状软组织肉瘤结构域蛋白ASPC抗体domain protein 9; UBX domain-containing protein 9; UBXD 9; UBXD9; UBXN 9; UBXN9.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, .

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Immunogen: KLH conjugated synthetic peptide derived from human TUG/ASPC.

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腺泡状软组织肉瘤结构域蛋白ASPC抗体Predicted Molecular Weight: 60kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.