酪氨酸蛋白磷酸酶非受体型12抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 酪氨酸蛋白磷酸酶非受体型12抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, 酪氨酸蛋白磷酸酶非受体型12抗体and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1,酪氨酸蛋白磷酸酶非受体型12抗体 and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

Also known as:

Protein tyrosine phosphatase G1; Protein tyrosine phosphatase non receptor type 12; Protein-tyrosine phosphatase酪氨酸蛋白磷酸酶非受体型12抗体 G1; PTN12_HUMAN; PTP PEST; PTP-PEST; PTPG1; Ptpn12; Tyrosine protein phosphatase non receptor type 12; Tyrosine-protein phosphatase non-receptor type 12.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human PTPN12.

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酪氨酸蛋白磷酸酶非受体型12抗体Predicted Molecular Weight: 88kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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