磷酸化果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

6 Phosphofructo 2 Kinase plays a role in the synthesis and degradation of fructose 2,6-bisphosphate. Fructose-2,6-bisphosphate acts as an allosteric regulator of 6-phosphofructo-1-kinase (PFK1),磷酸化果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体 which catalyses a key step in the glycoytic pathway. Glycolytic flux is key to tumour growth, and small molecule inhibition of 6 Phosphofructo 2 Kinase suppresses both glycolytic flux and tumour growth. Several lines of evidence suggest that 6 Phosphofructo 2 Kinase is also involved in obesity.

磷酸化果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体Also known as:

6 phosphofructo 2 kinase/ fructose 2,6 bisphosphatase; 6 phosphofructo 2 kinase/fructose 2,6 biphosphatase 3; 6PF 2 K/Fru 2,6 P2ASE brain/placenta type isozyme; 6PF 2-K/Fru 2,6 P2ase 3; fructose 6 phosphate,2 kinase/fructose 2, 6 bisphosphatase; Inducible 6 phosphofructo 2 kinase/fructose 2,6 bisphosphatase; iPFK 2; IPFK2; PFK/FBPase 3; PFK-2; PFK2; Renal carcinoma antigen NY REN 56; uPFK 2; PFKFB3; F263_HUMAN.

Specificity:

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Rabbit Polyclonal IgG,磷酸化果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human PFK2 around the phosphorylation site of Ser467.

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Predicted Molecular Weight: 60kDa.

磷酸化果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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