纺锤体检查点蛋白抗体

?纺锤体检查点蛋白抗体Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Bub1 was initially identified as the mammalian homolog to the yeast protein through a cDNA screen. Bub1 encodes a kinase involved in the formation of the spindle checkpoint, 纺锤体检查点蛋白抗体an important mechanism that ensures high fidelity mitotic chromosome segregation. It is thought to be required for assembly of a functional inner centromere, sister chromatid cohesion via targeting of the Shugoshim protein and metaphase congression. Bub1 functions by phosphorylating cdc20, a member of the mitotic checkpoint complex and activating the spindle checkpoint.纺锤体检查点蛋白抗体 A related protein kinase Bub3 interacts with Bub1 and targets it to kinetochores prior to chromosome alignment. Mutations in bub1 have been associated with aneuploidy and several forms of cancer.

Also known as:

Bub1; BUB1 budding uninhibited by benzimidazoles 1 homolog; BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast); BUB1_HUMAN; BUB1A; BUB1L; Budding uninhibited by benzimidazoles 1 (yeast homolog);纺锤体检查点蛋白抗体 Budding uninhibited by benzimidazoles 1 homolog; hBUB1; Mitotic checkpoint serine/threonine protein kinase BUB1; Mitotic checkpoint serine/threonine-protein kinase BUB1; Mitotic spindle checkpoint kinase; Putative serine/threonine protein kinase.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, .

●

Immunogen: KLH conjugated synthetic peptide derived from human Bub1.

●

纺锤体检查点蛋白抗体Predicted Molecular Weight: 122kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl477Hu01外生骨疣样蛋白1(EXTL1)多克隆抗体Polyclonal Antibody to Exostoses Like Protein 1 (EXTL1)

kl487Hu01真核翻译起始因子6(EIF6)多克隆抗体Polyclonal Antibody to Eukaryotic Translation Initiation Factor 6 (EIF6)

kl507Hu01序列相似家族3成员B(FAM3B)多克隆抗体Polyclonal Antibody to Family With Sequence Similarity 3, Member B (FAM3B)

kl507Mu01序列相似家族3成员B(FAM3B)多克隆抗体Polyclonal Antibody to Family With Sequence Similarity 3, Member B (FAM3B)

kl514Ra01丝蛋白结合LIM蛋白1(FBLIM1)多克隆抗体Polyclonal Antibody to Filamin Binding LIM Protein 1 (FBLIM1)

kl523Hu01FK506结合蛋白样蛋白(FKBPL)多克隆抗体Polyclonal Antibody to FK506 Binding Protein Like Protein (FKBPL)

kl534Hu01生长停滞DNA损伤可诱导蛋白α(GADD45α)多克隆抗体Polyclonal Antibody to Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a)

kl534Ra01生长停滞DNA损伤可诱导蛋白α(GADD45α)多克隆抗体Polyclonal Antibody to Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a)

kl548Hu01胶质细胞系来源神经营养因子受体α1(GFRα1)多克隆抗体Polyclonal Antibody to Glial Cell Line Derived Neurotrophic Factor Receptor Alpha 1 (GFRa1)

kl575Hu01颗粒酶H(GZMH)多克隆抗体Polyclonal Antibody to Granzyme H (GZMH)

kl604Hu01HtrA丝氨酸肽酶1(HTRA1)多克隆抗体Polyclonal Antibody to HtrA Serine Peptidase 1 (HTRA1)

kl617Hu01胰岛素样生长因子2-mRNA结合蛋白3(IGF2BP3)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3)

kl621Hu01白介素1家族成员9(IL1F9)多克隆抗体Polyclonal Antibody to Interleukin 1 Family, Member 9 (IL1F9)

kl621Mu01白介素1家族成员9(IL1F9)多克隆抗体Polyclonal Antibody to Interleukin 1 Family, Member 9 (IL1F9)

kl624Hu01107kDa肌醇多聚磷酸-4-磷酸酶Ⅰ型(INPP4A)多克隆抗体Polyclonal Antibody to Inositol Polyphosphate-4-Phosphatase Type I 107kDa (INPP4A)