细胞周期后期促进蛋白亚基10抗体Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Composed of more than ten subunits, the anaphase-promoting complex (APC) acts in a cell-cycle dependent manner to promote the separation of sister chromatids during the transition between metaphase and anaphase in mitosis. APC, or cyclosome, accomplishes this progression through the ubiquitination of mitotic cyclins and other regulatory proteins that are targeted for destruction during cell 细胞周期后期促进蛋白亚基10抗体division. APC is phosphorylated, and thus activated, by protein kinases Cdk1/cyclin B and polo-like kinase (Plk). APC is under tight control by a number of regulatory factors, including CDC20, CDH1 and MAD2. Specifically, CDC20 and CDH1 directly bind to and activate the cyclin-ubiquitination activity of APCs. In contrast, MAD2 inhibits APC by forming a ternary complex with CDC20 and APC, thus preventing APC activation. APC10 contains a Doc1 homology domain, which is a beta-sandwich structure common to many other putative E3 ubiquitin ligases.细胞周期后期促进蛋白亚基10抗体 APC10 binds to core APC subunits throughout the cell cycle. Specifically, APC10 binds to the C-terminus of CDC27/APC3. During mitosis, APC10 is localized in centrosomes and mitotic spindles. APC10 also localizes to kinetochores from prophase to anaphase, and to the midbody in telophase and cytokinesis.
Also known as:
细胞周期后期促进蛋白亚基10抗体ANAPC 10; anapc10; Anaphase promoting complex 10; Anaphase promoting complex subunit 10; Anaphase-promoting complex subunit 10; Apc 10; APC10; APC10_HUMAN; Cyclosome subunit 10; DKFZP564L0562; Doc 1; Doc1; OTTHUMP00000220297; OTTHUMP00000220298; OTTHUMP00000220299; OTTHUMP00000220300; OTTHUMP00000220303.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human APC10.
●
Predicted Molecular Weight: 21kDa.
细胞周期后期促进蛋白亚基10抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl226Hu01胃脂酶(LIPF)多克隆抗体Polyclonal Antibody to Likle, Gastric (LIPF)
kl226Mu01胃脂酶(LIPF)多克隆抗体Polyclonal Antibody to Likle, Gastric (LIPF)
kl226Ra01胃脂酶(LIPF)多克隆抗体Polyclonal Antibody to Likle, Gastric (LIPF)
kl226Po01胃脂酶(LIPF)多克隆抗体Polyclonal Antibody to Likle, Gastric (LIPF)
kl469Hu01内皮脂肪酶(LIPG)多克隆抗体Polyclonal Antibody to Likle, Endothelial (LIPG)
kl469Mu01内皮脂肪酶(LIPG)多克隆抗体Polyclonal Antibody to Likle, Endothelial (LIPG)
kl469Ra01内皮脂肪酶(LIPG)多克隆抗体Polyclonal Antibody to Likle, Endothelial (LIPG)
kl176Hu01脂肪酶I(LIPI)多克隆抗体Polyclonal Antibody to Likle I (LIPI)
kl176Mu01脂肪酶I(LIPI)多克隆抗体Polyclonal Antibody to Likle I (LIPI)
kl176Ra01脂肪酶I(LIPI)多克隆抗体Polyclonal Antibody to Likle I (LIPI)
kl175Hu01脂肪酶H(LIPH)多克隆抗体Polyclonal Antibody to Likle H (LIPH)
kl175Mu01脂肪酶H(LIPH)多克隆抗体Polyclonal Antibody to Likle H (LIPH)
kl386Hu01脂蛋白脂酶(LIPD)多克隆抗体Polyclonal Antibody to Likle, Lipoprotein (LIPD)
kl386Mu01脂蛋白脂酶(LIPD)多克隆抗体Polyclonal Antibody to Likle, Lipoprotein (LIPD)
kl386Ra01脂蛋白脂酶(LIPD)多克隆抗体Polyclonal Antibody to Likle, Lipoprotein (LIPD)
kl225Hu01溶酶体酸脂肪酶A(LIPA)多克隆抗体Polyclonal Antibody to Likle A, Lysosomal Acid (LIPA)
kl225Mu01溶酶体酸脂肪酶A(LIPA)多克隆抗体Polyclonal Antibody to Likle A, Lysosomal Acid (LIPA)
kl225Ra01溶酶体酸脂肪酶A(LIPA)多克隆抗体Polyclonal Antibody to Likle A, Lysosomal Acid (LIPA)
kl526Ge01脂多糖(LPS)多克隆抗体Polyclonal Antibody to Lipopolysaccharide (LPS)
kl082Hu01层粘连蛋白γ1(LAMγ1)多克隆抗体Polyclonal Antibody to Laminin Gamma 1 (LAMC1)
更多
企业名称
上海康朗生物科技有限公司
企业信息已认证
企业类型
信用代码
310112001510759
成立日期
2015-05-29
注册资本
100
经营范围
从事生物科技技术领域内技术开发、技术咨询、技术服务、技术转让,实验分析仪器、化工产品及原料(除危险化学品、监控化学品、烟花爆竹、民用爆竹物品、易制毒化学品)、仪器仪表、环保设备、酒店用品、皮革制品、床上用品、电子产品的销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海康朗生物科技有限公司
公司地址
上海市闵行区闵北路88弄1-30号第22栋BV145室
客服电话