Butein

Chemical Name:   Butein

Catalogue Number:   B690125

Synonyms:   (2E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one; 2',3,4,4'-Tetrahydroxychalcone;

CAS Number:   487-52-5

Possible CAS Number:   NA

Mol. Formula:   C15H12O5

Appearance:   Yellow Solid

Melting Point:   208-213°C

Mol. Weight:   272.25

Storage:   Hygroscopic, -20?C Freezer, Under Inert Atmosphere

Stability:   No Data Available

Solubility:   Methanol

Boiling Point:   No Data Available

Category:   Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals

Applications:   Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-κB in activated human mast cells: suppression of tumor necrosis factor-α, interleukin (IL)-6, and IL-8. Anti-inflammatory agent.

References:   Woolley, D., et al.: Arthritis Res., 2, 65 (2000), Huang, D., et al.: J. Agric. Food Chem., 50, 4437 (2002), Lee, D., et al.: Science, 297, 1689 (2002),