Chemical Name: Butein
Catalogue Number: B690125
Synonyms: (2E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one; 2',3,4,4'-Tetrahydroxychalcone;
CAS Number: 487-52-5
Possible CAS Number: NA
Mol. Formula: C15H12O5
Appearance: Yellow Solid
Melting Point: 208-213°C
Mol. Weight: 272.25
Storage: Hygroscopic, -20?C Freezer, Under Inert Atmosphere
Stability: No Data Available
Solubility: Methanol
Boiling Point: No Data Available
Category: Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Applications: Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-κB in activated human mast cells: suppression of tumor necrosis factor-α, interleukin (IL)-6, and IL-8. Anti-inflammatory agent.
References: Woolley, D., et al.: Arthritis Res., 2, 65 (2000), Huang, D., et al.: J. Agric. Food Chem., 50, 4437 (2002), Lee, D., et al.: Science, 297, 1689 (2002),