Chemical Name: Bergamottin
Catalogue Number: B318400
Synonyms: 4-[[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one; (E)-4-[(3,7-dimethyl-2,6-octadienyl)oxy]-H-furo[3,2-g][1]benzopyran-7-one; 5-Geranoxypsoralen; Bergamotine; Bergaptin;
CAS Number: 7380-40-7
Possible CAS Number: NA
Mol. Formula: C21H22O4
Appearance: Off-White to Pale Yellow Solid
Melting Point: 53-55°C
Mol. Weight: 338.4
Storage: -20?C Freezer
Stability: No Data Available
Solubility: Chloroform, DMSO, Methanol
Boiling Point: No Data Available
Category: Amines, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Applications: Bergamottin (BG), a component of grapefruit juice, is a mechanism-based inactivator of CYP3A4 and contributes, in part, to the grapefruit juice-drug interaction.
References: Bailey, D., et al.: Clin. Pharmacol. Ther., 68, 468 (2000), Guo, L., et al.; Drug Metab. Dispos., 28, 766 (2000), Baer, B., et al.: Chem. Res. Toxicol., 20, 954 (2007), Lin, H., et al.: Drug Metab. Dispos., 39, 24 (2011);