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当前位置: 基免 > 最新动态 > 精子尾部结构蛋白抗体生产厂家说明

精子尾部结构蛋白抗体生产厂家说明

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2014/12/19 09:40

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精子尾部结构蛋白抗体别名:sperm tail structural protein; 84 kDa outer dense fiber protein; Cenexin 1; Cenexin1 variant 1; KKT 4; KKT4; ODF 2; ODF 84; ODF2; ODF2/1; ODF2/2; ODF84; Outer dense fiber of sperm tail 2; Outer dense fiber of sperm tails 2; outer dense fiber of sperm tails; Outer dense fiber of sperm tails protein 2; Outer dense fiber of sperm tails, 84 kD; Outer dense fiber protein 2; Sperm outer dense fiber major protein 2; Testis specific autoantigen; ODFP2_HUMAN. 

浓度:1mg/1ml 

规格:0.1ml/100μg  0.2ml/200μg

抗体来源:Rabbit  

克隆类型:polyclonal 

交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Horse

产品类型:一抗    

研究领域:免疫学 发育生物学 信号转导  

蛋白分子量:predicted molecular weight: 91kDa 

精子尾部结构蛋白抗体性状:Lyophilized or Liquid 

免疫原:KLH conjugated synthetic peptide derived from human ODF2 

亚型:IgG 

纯化方法:affinity purified by Protein A 

储存液:0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide 

产品应用:IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 

(石蜡切片需做抗原修复) 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍:Cenexin1 is an isoform of ODF2, that unlike ODF2 is present in several somatic cell types. Cenexin1 acts as a general scaffold protein that is specifically localised to the distal/subdistal appendages of mother centrioles. Cenexin1 is required for proper localization of Plk1 to the centrosomes. This centrosomal localization of Plk1 is required for proper microtubule function. Cenexin1 recruits Plk1 via a C-terminal extension of cenexin1 that is not present in ODF2. Cenexin1 is required for proper mitotic progression; depletion of Cenexin1 ultimately leads to chromosome missegregation and apoptosis. The ODF2 (outer dense fiber 2) gene encodes both ODF2 and Cenexin1, which have very different functions. ODF2 is a major component of sperm tail outer dense fibers (ODFs). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. They may help to maintain the passive elastic structures and elastic recoil of the sperm tail, and may also modulate sperm motility.

Function : Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.

Subunit : Self-associates. Associates with microtubules and forms a fibrillar structure partially linked to the microtubule network. Interacts via its C-terminus with PLK1. Interacts with ODF1.

Subcellular Location : Cytoplasm, cytoskeleton, centrosome. Cell projection, cilium. Cytoplasm, cytoskeleton, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Note=Localized at the microtubule organizing centers in interphase and spindle poles in mitosis. Localized at the distal/subdistal appendages of mother centrioles.

Tissue Specificity : Testis-specific (at protein level). Highly expressed in cytoplasm of step 2 round spermatids. Detected in the middle piece and extends to about half the principal piece of the sperm tails.

Post-translational modifications : Tyrosine phosphorylated.

Similarity : Belongs to the ODF2 family.

Database links : UniProtKB/Swiss-Prot: Q5BJF6.1

E-(Hu)(02)-03351 内皮素-1(ET-1)Elisa试剂盒 ,英文名: ET-1 ELISA KIT ,规格: 96T/48T

E-(Hu)(02)-03352 内皮素(ET-1)Elisa试剂盒 ,英文名: Endothelin-1 ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03353 内毒素(endotoxin)Elisa试剂盒 ,英文名: endotoxin ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03354 脑源性神经营养因子(BDNF)Elisa试剂盒 ,英文名: Brain derived neurotrophic facor ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03355 脑钠素(BNP)Elisa试剂盒 ,英文名: BNP ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03356 脑肠肽(Gehrelin)Elisa试剂盒 ,英文名: Gehrelin Elisa kit ,规格: 96T/48T

E-(Hu)(02)-03357 苗条素受体(Leptin receptor)Elisa试剂盒 ,英文名: Leptin receptor ELISA kit ,规格: 96T/48T

E-(Hu)(02)-03358 免疫球蛋白M(IgM)Elisa试剂盒 ,英文名: IgM ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03359 免疫球蛋白IgEElisa试剂盒 ,英文名: IgE ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03360 免疫球蛋白G(IgG)Elisa试剂盒 ,英文名: IgG ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03361 免疫球蛋白E(IgE)Elisa试剂盒 ,英文名: IgE ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03362 免疫球蛋白A(IgA)Elisa试剂盒 ,英文名: IgA ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03363 卵泡抑素(FS)Elisa试剂盒 ,英文名: Follistatin ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03364 磷脂酰肌醇三羟基激酶(PI3K)Elisa试剂盒 ,英文名: Phosphoinositide-3 kinase ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03365 磷脂酶A2(PLA2)Elisa试剂盒 ,英文名: Phospholipidase A2 ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03366 粒细胞克隆刺激因子(G-CSF)Elisa试剂盒 ,英文名: G-CSF ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03367 粒细胞巨噬细胞集落刺激因子(GM-CSF)Elisa试剂盒 ,英文名: Granulocyte-Macrophage Colony Stimulating Factor ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03368 可溶性血小板-内皮细胞粘附分子(sPECAM-1)Elisa试剂盒 ,英文名: sPECAM-1 ELISA KIT ,规格: 96T/48T

E-(Hu)(02)-03369 可溶性血管细胞粘附分子(sVCAM-1)Elisa试剂盒 ,英文名: sVCAM-1 ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03370 可溶性细胞间粘附分子-1(sICAM-1)Elisa试剂盒 ,英文名: sICAM-1 ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03371 可溶性破骨细胞异化因子(sPANKL)Elisa试剂盒 ,英文名: sPANKL ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03372 可溶性sP-选择素(sP-selectin)Elisa试剂盒 ,英文名: sP-selectin ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03373精子尾部结构蛋白抗体可溶性E-选择素(sE-selectin[CD-62E])Elisa试剂盒 ,英文名: sE-selectin[CD-62E] ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03374 可溶性CD40配体(sCD40L)Elisa试剂盒 ,英文名: Soluble CD40 ligand ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03375 抗子宫内膜抗体(AEA)Elisa试剂盒 ,英文名: AEA(IgG,M) ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03376 抗中性粒细胞胞浆抗体(甲醛固定)(pANCA)Elisa试剂盒 ,英文名: pANCA ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03377 抗心肌抗体IgM(HRAb IgM)Elisa试剂盒 ,英文名: HRAb IgM ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03378 抗心肌抗体IgG(HRAb IgG)Elisa试剂盒 ,英文名: HRAb IgG ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03379 抗心肌抗体(CMA)Elisa试剂盒 ,英文名: anticardiacmuscle antibody ELISA Kit ,规格: 96T/48T

E-(Hu)(02)-03380 抗嗜中性粒细胞胞浆抗体(ANCA)Elisa试剂盒 ,英文名: ANCA ELISA Kit ,规格: 96T/48T


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