钠离子/牛磺胆酸共转运蛋白抗体
[别名:Na+/taurocholate Cotransporting Polypeptide; Na(+)/bile acid cotransporter; Cell growth-inhibiting gene 29 protein; Na / bile acid cotransporter; Na / taurocholate transport protein; Na(+)/taurocholate transport protein; NTCP; NTCP1; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1; Slc10a1 protein; Slc10a1; SBACT.
[产品介绍:钠离子/牛磺胆酸共转运蛋白抗体Sodium/bile acid cotransporters are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids, one absorbing from the intestinal lumen, the bile duct, and the kidney with an apical localization(SLC10A2; MIM 601295), and the other being found in the basolateral membranes of hepatocytes (SLC10A1).[supplied by OMIM:
Function : The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium.
Subcellular Location : Membrane; Multi-pass membrane protein.
Tissue Specificity : Liver and kidney
Similarity : Belongs to the sodium:bile acid symporter family.
NTCP(钠离子/牛磺胆酸共转运蛋白)(钠离子-牛磺胆酸共转运多肽)Na+/taurocholate Cotransporting Polypeptide是肝脏的胆汁酸盐吸收主要是钠离子依赖性转运子NTCP介导的,主要吸收牛磺胆酸,是肝细胞特有的一种转运载体,分布在肝细胞基侧膜在肝小叶和肝的腺泡表达较多。
有学者认为:NTCP是乙肝病毒的细胞表面受体分子,是HBV和HDV的功能受体,这些研究将有待于科研人员的进一步证实。
规格:多种抗体规格提供
贮存: 贮存于-20℃
纯化方法:亲和纯化的蛋白
研究领域:细胞生物 免疫学 锌指蛋白
产品应用比例:WB=1:100-500 Elisa=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1/20-1/100
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