核呼吸因子-1抗体
[别名:erythroid derived 2; like 1; Locus control region factor 1; Locus control region-factor 1; NF-E2-related factor 1; NF2L1_HUMAN; NFE2 related factor 1; NFE2-related factor 1; NFE2L1; NRF1; NRF-1; NRF 1; Nuclear factor; Nuclear factor erythroid 2-related factor 1; Nuclear factor erythroid derived 2 like 1; TCF-11; TCF11; Transcription factor 11; Transcription factor HBZ17; Transcription factor LCR F1; Transcription factor LCR-F1.
[产品介绍:核呼吸因子-1抗体This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1. [provided by RefSeq:.
Function : Activates erythroid-specific, globin gene expression.
Subunit : Interacts with KEAP1.
Subcellular Location : Endoplasmic reticulum membrane; Single-pass type II membrane protein. Nucleus.
Similarity : Belongs to the bZIP family. CNC subfamily.
Contains 1 bZIP (basic-leucine zipper) domain.
Database links : UniProtKB/Swiss-Prot: Q14494.1
Entrez Gene: 4899 Human
Omim: 600879 Human
SwissProt: Q16656 Human
Unigene: 654363 Human
NRF-1是核基因编码且影响mtDNA的另一重要因子, 他控制着线粒体电子传递链的一些蛋白质的合成。
规格:多种抗体规格提供
贮存: 贮存于-20℃
纯化方法:亲和纯化的蛋白
研究领域:细胞生物 免疫学 锌指蛋白
产品应用比例:WB=1:100-500 Elisa=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1/20-1/100
公司生产的核呼吸因子-1抗体每个流程都执行严格的检测标准,保证蛋白抗原产品质量,质量稳定,实验效果明显。按理化性质和生物学功能,可将其分为IgM、IgG、IgA、IgE、IgD五类。公司产品经无数次市场验证,若出现质量问题可无条件换货或退货。本司备有上万种产品,所有生化试剂产品都具有价格绝对优势,质量保证,欢迎新老客户垂询!