雷帕霉素靶蛋白抗体

雷帕霉素靶蛋白抗体

产品标准

 浓缩液(1mg/1ml) 亲和纯化抗体

雷帕霉素靶蛋白抗体产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

雷帕霉素靶蛋白抗体产品介绍

   mTOR蛋白是一种丝氨酸／苏氨酸蛋白激酶（Ser/Thr），是调节细胞生长和增殖的重要信号转导分子，在细胞的生长、分化、增殖、迁移和存活上扮演了重要的角色。由于mTOR信号通路在细胞周期进程中发挥了重要作用，细胞周期进程调节异常与许多疾病尤其是癌症的发生、发展有关，mTOR信号通路的失调可引起多种肿瘤的发生。

    mTOR is one of a family of proteins involved in cell cycle progression, DNA recombination, and DNA damage detection. In rat, it is a 289-kDa protein (symbolized RAFT1) with significant homology to the Saccharomyces cerevisiae protein TOR1 and has been shown to associate with the immunophilin FKBP12 in a rapamycin dependent fashion. The FKBP12-rapamycin complex is known to inhibit progression through the G1 cell cycle stage by interfering with mitogenic signaling pathways involved in G1 progression in several cell types, as well as in yeast. The binding of FRAP to FKBP12-rapamycin correlated with the ability of these ligands to inhibit cell cycle progression. 
    mol wt:280kDa 
    Other Aliases: 
    Mammalian target of rapamycin; FKBP12 rapamycin associated protein; dJ576K7.1; FK506 binding protein 12 rapamycin associated protein 1; FK506 binding protein 12 rapamycin associated protein 2; FKBP rapamycin associated protein; FKBP12 rapamycin complex associated protein; FLJ44809; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; MTOR; OTTHUMP00000001983; RAFT1; Rapamycin associated protein FRAP2; Rapamycin target protein; RAPT1; 2610315D21Rik; AI327068; flat

xy-10309R Cenexin1精子尾部结构蛋白抗体

xy-15198R C5orf19 5号染色体开放阅读框19抗体

雷帕霉素靶蛋白抗体

xy-15313R C9orf1399号染色体开放阅读框139抗体

xy-15314R C9orf1409号染色体开放阅读框140抗体

xy-15315R C9orf1429号染色体开放阅读框142抗体

xy-15317R C9orf1639号染色体开放阅读框163抗体

xy-15318R C9orf1699号染色体开放阅读框169抗体

xy-15321R C9orf173 9号染色体开放阅读框173抗体

xy-15322R C9orf219号染色体开放阅读框21抗体

xy-10225R phospho-CK II beta (Ser209)磷酸化丝氨酸/苏氨酸蛋白激酶II β/casein kinase IIβ抗体

xym-4792M CEA癌胚抗原抗体

xym-4793M CEA癌胚抗原抗体

xy-12323R CDON细胞粘附分子相关蛋白/癌基因下调蛋白抗体

xy-12327R CD59淋巴细胞抗原Ly6c抗体

xy-8929R Cyclin E周期素E抗体

xy-15272R C7ORF507号染色体开放阅读框50抗体

xy-15273R C7orf537号染色体开放阅读框53抗体

xy-15275R C7orf597号染色体开放阅读框59抗体

xy-15279R C7orf647号染色体开放阅读框64抗体

xy-15283R C8orf128号染色体开放阅读框12抗体

xy-15285R C8orf318号染色体开放阅读框31抗体

xy-15286R C8orf338号染色体开放阅读框33抗体

xy-8859R Collagen IIⅡ型胶原蛋白抗体

xy-12356R Alx1软骨蛋白1抗体

xy-12357R CFDP1颅面部发育蛋白1抗体

xy-12338R CPA3肥大细胞羧肽酶A3抗体

xy-15003R C1orf105 1号染色体开放阅读框105抗体

xy-10144R CD35Ⅰ型补体受体抗体（C3b/C4b受体抗体）

xy-10183R CMKLR1趋化样因子受体1抗体

xy-10185R CMKLR1趋化样因子受体1抗体

xy-12583R phospho-beta Catenin (Ser33)磷酸化β-连环蛋白/β-连环素/β链接素抗体

xy-12854R phospho-beta Catenin (Ser37)磷酸化β-连环蛋白/β-连环素/β链接素抗体

xy-12855R phospho-beta Catenin (Thr41)磷酸化β-连环蛋白/β-连环素/β链接素抗体

xy-12856R phospho-beta Catenin (Tyr333)磷酸化β-连环蛋白/β-连环素/β链接素抗体

xy-12857R phospho-beta Catenin (Tyr489)磷酸化β-连环蛋白/β-连环素/β链接素抗体

xy-12858R phospho-beta Catenin (Tyr86)磷酸化β-连环蛋白/β-连环素/β链接素抗体