抗GATA结合蛋白4抗体

抗GATA结合蛋白4抗体

产品类别

 兔抗人、大、小鼠GATA4抗体

抗GATA结合蛋白4抗体

产品标准

 浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

 WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

 抗GATA结合蛋白4抗体

产品介绍

 GATA-4属于转录调节性因子，表达在心组织、胃肠道组织中，并调节该类T细胞的发育和功能。
 GATA4 is a 46 kDa member of the GATA family of zinc finger containing transcription factors that is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress induced gene expression in cardiac and smooth muscle cell types. GATA4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain. Serine 105 of GATA4 is phosphorylated in response to agonist stimulation through MEK 1 ERK1 / 2, and weakly through JNK or p38 MAPKs.
 mol wt:48kDa 
 Other Aliases: 
 GATA binding factor 4; Transcription factor GATA-4; GATA-binding factor 4; Gata4.

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