抗切除修复交叉互补基因1抗体

抗切除修复交叉互补基因1抗体

产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

抗切除修复交叉互补基因1抗体产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

抗切除修复交叉互补基因1抗体产品说明

    ERCC1蛋白是动物内重要的DNA修复基因家族成员之一。在人体内它的低表达往往伴随着基因不稳定性增加,从而产生肿瘤恶性变的发生。

    The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. 
    mol wt:36kDa 
    Other Aliases: 
    Excision Repair Cross Complementing 1; DNA excision repair protein ERCC-1; COFS4; UV20; DNA excision repair protein ERCC1; ERCC 1; Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1; Excision repair protein; UV 20; UV20

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xy-11594R Nicalinγ-分泌酶组件蛋白NCLN抗体

抗切除修复交叉互补基因1抗体

xy-11572R NR2E3核受体蛋白NR2E3抗体

xy-7815R NEK8丝氨酸/苏氨酸蛋白激酶NEK8抗体

xy-7819R NUP37核孔蛋白Nup37抗体

xy-7816R NSP5核结构蛋白5抗体

xy-7817R NUBP1核苷酸结合蛋白1抗体

xy-7818R NUBP2核苷酸结合蛋白2抗体

xy-7757R NAT10乙酰基转移酶10抗体

xy-7758R NEK7丝氨酸/苏氨酸蛋白激酶Nek7抗体

xy-4142R NPTX1神经细胞正五聚体1抗体

xy-5097R NNT烟酰胺核苷酸转氢酶抗体

xy-2348R Natriuretic Peptide Receptor B利钠肽受体B抗体

xy-2333R NPRC利钠肽受体C抗体

xy-5381R Phospho-NMDAR2B (Tyr1336)磷酸化谷氨酸受体2B抗体

xy-5380R Phospho-NMDAR2B (Tyr1252)磷酸化谷氨酸受体2B抗体

xy-3889R NOX2NADPH氧化酶2抗体

xy-3891R NOXA2NADPH氧化酶活化蛋白1抗体

xy-5660R phospho-NFKB p65(Ser529)磷酸化细胞核因子抗体

xy-5661R phospho-NFKB p65(Thr435)磷酸化细胞核因子抗体

xy-5662R phospho-NFKB p65(Thr254)磷酸化细胞核因子抗体

xy-5663R phospho-NFKB p65(Thr505)磷酸化细胞核因子抗体

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xy-11524R NHLH2螺旋环螺旋蛋白2抗体

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xy-12273R NOBOX同源盒蛋白NOBOX抗体

xy-12247R NAC1转录因子NAC1抗体

xy-7122R NGFR神经生长因子受体抗体

xy-5517R phospho-IKB epsilon (Ser157)磷酸化KB抑制蛋白激酶ε

xy-5519R phospho-NRP1(Thr916)磷酸化神经纤毛蛋白1抗体

xy-4140R NF11型神经纤维瘤抗体

xy-5520R phospho-NF1(Ser2515)磷酸化1型神经纤维瘤抗体

xy-4141R NUDEL中心粒蛋白Nudel抗体

xy-5522R phospho-NDEL1(Ser231)磷酸化中心粒蛋白Nudel抗体

xy-5088R NSDHL类固醇脱氢酶样蛋白NSDHL抗体

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