抗细胞角蛋白7抗体(大、小鼠)

供货周期：现货

品牌： CST

规格： g/mg

货号： XY-1610R

CAS号：

报价：面议

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产品介绍

抗细胞角蛋白7抗体(大、小鼠)

产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

抗细胞角蛋白7抗体(大、小鼠)产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

抗细胞角蛋白7抗体(大、小鼠)产品介绍

    结构蛋白（Structural Proteins）
    CK-7是一种 54KDa 的中间丝蛋白，存在于大多数正常组织的腺上皮和移行上皮细胞中。该抗体与多种良/恶性上皮性肿瘤反应。腺癌中的卵巢、乳腺、肺的腺癌呈阳性反应，而胃肠道的腺癌阴性。移行细胞肿瘤、前列腺癌也呈阳性反应。通常认为 CK7是腺癌和移行上皮细胞癌的比较特异性的标志。
         Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 – 7.8. The individual human cytokeratins are designated 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

    <cytokeratin 54kd="" intermediate="" filament="" protein="" a="" variety="" glandularepithelia.="" has="" been="" found="" columnar="" glandular="" epithelium="" lung,="" cervix,="" breast,="" bile="" larger="" collecting="" ducts="" kidney.="" it="" present="" in="" transitional="" epitheliumof="" bladder="" well="" as="" ovarian="" lungepithelia,="" and="" occasionally="" staining="" blood="" vessel="" cell="" walls,="" particularly="" endothelial="" cells,="" may="" be="" observed.="" however,="" cytokeratin="" not="" by="" epithelial="" cells="" of="" the="" gastrointestinal="" tract,="" colon="" or="" prostate.="" keratin="" 7="" is="" often="" co="" expressed="" with="" 19.
    Also known as:
    Cytokeratin 7; CK 7; K7; Keratin 7; Keratin,type II cytoskeletal 7; KRT7; SCL

xy-13152R FCHO1FCHO1蛋白抗体

xy-13063R phospho-FABP4 (Tyr20)磷酸化脂肪细胞型脂肪酸结合蛋白

xy-13064R FABP12脂肪酸结合蛋白12抗体

xy-12404R FJX1四连接同源蛋白FJX1抗体

抗细胞角蛋白7抗体(大、小鼠)

xy-13244R G gamma3G蛋白偶联受体γ3抗体

xy-13246R G gamma7G蛋白偶联受体γ7抗体

xy-13247R G protein alpha 13G蛋白结合蛋白α13/Gα13抗体

xy-13248R G protein alpha 16G蛋白结合蛋白α16/Gα16抗体

xy-13249R G protein alpha inhibitor 1G蛋白α抑制剂抗体

xy-13250R G Protein alpha x+zG蛋白受体α x+z抗体

xy-13251R GALC/Galactosylceramidase半乳糖神经酰胺酶抗体